Diseases & Conditions


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Adult Onset Still?s Disease


Synonyms of Adult Onset Still?s Disease
  • Adult Still?s Disease
  • AOSD
  • Wissler-Fanconi Syndrome

Disorder Subdivisions



    General Discussion
    Adult onset Still?s disease (AOSD) is a rare inflammatory disorder that affects the entire body (systemic disease). The cause of the disorder is unknown (idiopathic). Affected individuals may develop episodes of high, spiking fevers, a pink or salmon colored rash, joint pain, muscle pain, a sore throat and other symptoms associated with systemic inflammatory disease. The specific symptoms and frequency of episodes vary from one person to another and the progression of the disorder is difficult to predict. In some individuals, the disorder appears suddenly, disappears almost as quickly and may not return. In other people, adult onset Still?s disease is a chronic, potentially disabling, condition. Various medications are used to treat individuals with adult onset Still?s disease; affected individuals may respond to therapy differently. Adult onset Still?s disease does not appear to run in families.

    Adult onset Still?s disease is the adult form of systemic juvenile rheumatoid arthritis (juvenile Still?s disease). The disorders are name after a British physician who first described systemic juvenile rheumatoid arthritis in the medical literature in 1896. The term ?adult Still?s disease? was first used in the medial literature in 1971, but cases that fit the description of the disorder appear in the medical literature as early as the late 1800s.

    Organizations related to Adult Onset Still?s Disease
    • Arthritis Foundation
      1330 West Peachtree Street
      Atlanta GA 30309
      Phone #: 404-872-7100
      800 #: 800-568-4045
      e-mail: help@arthritis.org
      Home page: http://www.arthritis.org
    • Arthritis Society
      393 University Avenue
      Ontario Intl M5G IE6
      Phone #: 416-979-7228
      800 #: 800-321-1433
      e-mail: info@arthritis.ca
      Home page: http://www.arthritis.ca
    • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
      1 AMS Circle
      Bethesda MD 20892-3675
      Phone #: 301-495-4484
      800 #: 877-226-4267
      e-mail: NIAMSinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

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