Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aicardi Syndrome


Synonyms of Aicardi Syndrome
  • Agenesis of Corpus Callosum With Chorioretinitis Abnormality
  • Agenesis of Corpus Callosum With Infantile Spasms And Ocular Anomalies
  • Callosal Agenesis and Ocular Abnormalities
  • Chorioretinal Anomalies with ACC
  • Corpus Callosum, Agenesis of and Chorioretinal Abnormality

Disorder Subdivisions



    General Discussion
    Aicardi syndrome is an extremely rare genetic disorder. Almost all people with Aicardi syndrome are females. Individuals with Aicardi syndrome have agenesis of the corpus callosum, chorioretinal lacunae and seizures. Agenesis of the corpus callosum means that the structure that connects the right half of the brain with the left half of the brain (corpus callosum) does not develop normally. Chorioretinal lacunae are small holes in the retina (back part of the eye). These are only visible to a doctor using a device to look into the back of the eye. It is very unusual to have Aicardi syndrome without having chorioretinal lacunae. The seizures can be of different types. Infants with Aicardi syndrome usually have a type of seizures known as ?infantile spasms?. These are single jerks of the whole body. They may happen many times a day. Infants are usually awake during infantile spasms. These look different from the more common type of seizures known as ?generalized tonic-clonic? seizures. Generalized tonic-clonic seizures are rhythmic jerking of arms and legs. People often black out during this type of seizure. Children with Aicardi syndrome usually grow out of infantile spasms and then have generalized tonic-clonic seizures. Other parts of the brain also do not develop normally. These brain malformations cause frequent seizures and mental retardation.

    Organizations related to Aicardi Syndrome
    • Aicardi Syndrome Awareness and Support Group
      29 Delavan Avenue
      Ontario None M5P 1T2
      Phone #: (41-6) -481-4095
      800 #: --
      e-mail: asasn@sympatico.ca
      Home page: http://www.aicardisyndrome.org/
    • Aicardi Syndrome Foundation
      PO Box 3202
      St. Charles IL 60174
      Phone #: N/A
      800 #: 800-374-8518
      e-mail: foundation@aicardisyndrome.org
      Home page: http://www.aicardisyndrome.org
    • Aicardi Syndrome Newsletter, Inc.
      1510 Polo Fields Ct
      Louisville KY 40245
      Phone #: 502-244-9152
      800 #: --
      e-mail: AICNews@aol.com
      Home page: http://www.aicardisyndrome.org
    • Blind Children's Fund
      311 W. Broadway
      Mt. Pleasant MI 48858
      Phone #: 989-779-9966
      800 #: --
      e-mail: bcf@blindchildrensfund.org
      Home page: http://www.blindchildrensfund.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • March of Dimes Birth Defects Foundation
      1275 Mamaroneck Avenue
      White Plains NY 10605
      Phone #: 914-428-7100
      800 #: 888-663-4637
      e-mail: Askus@marchofdimes.com
      Home page: http://www.marchofdimes.com
    • National Association for Visually Handicapped
      22 West 21st Street
      New York NY 10010
      Phone #: 212-889-3141
      800 #: --
      e-mail: staff@navh.org
      Home page: http://www.navh.org
    • National Institute of Neurological Disorders and Stroke (NINDS)
      31 Center Drive
      Bethesda MD 20892-2540
      Phone #: 301-496-5751
      800 #: 800-352-9424
      e-mail: braininfo@ninds.nih.gov
      Home page: http://www.ninds.nih.gov/
    • The Arc (a national organization on mental retardation)
      1010 Wayne Ave
      Silver Spring MD 20910
      Phone #: 301-565-3842
      800 #: 800-433-5255
      e-mail: info@thearc.org
      Home page: http://www.thearc.org/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html