Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Allan Herndon Syndrome


Synonyms of Allan Herndon Syndrome
  • AHDS
  • Allan-Herndon-Dudley Mental Retardation
  • Allan-Herndon-Dudley Syndrome
  • X-Linked Mental Retardation with Hypotonia

Disorder Subdivisions



    General Discussion
    Allan-Herndon syndrome is an extremely rare inherited disorder that may be characterized by severe mental retardation, an impaired ability to form words and speak clearly (dysarthria), diminished muscle tone (hypotonia), and/or movement abnormalities.

    With the exception of poor muscle tone, most affected infants appear to develop normally during the first months of life. However, by about six months of age, affected infants may seem weak and have an inability to hold up the head. Due to hypotonia, severely reduced motor development, and other abnormalities, affected children may not develop the ability to walk or may walk with difficulty. Associated features often include underdevelopment (hypoplasia) and wasting (atrophy) of muscle tissue; weakness and stiffness of the legs (spastic paraplegia) with exaggerated reflexes (hyperreflexia); relatively slow, involuntary, purposeless, writhing movements (athetoid movements); and/or other movement abnormalities. Affected individuals may also have abnormalities of the skull and facial (craniofacial) region. Allan-Herndon syndrome is thought to be inherited as an X-linked recessive trait and therefore is typically fully expressed in males only.
    .

    Organizations related to Allan Herndon Syndrome
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • NIH/Nat'l Institute on Deafness & Other Communication Disorders Information Clearinghouse
      1 Communication Ave
      Bethesda MD 20892-3456
      Phone #: 301-402-0900
      800 #: 800-241-1044
      e-mail: nidcdinfo@nidcd.nih.gov
      Home page: http://www.nidcd.nih.gov
    • The Arc (a national organization on mental retardation)
      1010 Wayne Ave
      Silver Spring MD 20910
      Phone #: 301-565-3842
      800 #: 800-433-5255
      e-mail: info@thearc.org
      Home page: http://www.thearc.org/
    • WE MOVE (Worldwide Education and Awareness for Movement Disorders)
      204 West 84th Street
      New York NY 10024
      Phone #: 212-875-8312
      800 #: N/A
      e-mail: wemove@wemove.org
      Home page: http://www.wemove.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

    GÜNCEL SAĞLIK HABERLERİ

    Sizce hangisi en güçlü doğal antibiyotiktir? Katılım: 1652