Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Amyotrophic Lateral Sclerosis


Synonyms of Amyotrophic Lateral Sclerosis
  • ALS
  • Amyotrophic Lateral Sclerosis-Polyglucosan Bodies
  • Aran-Duchenne Muscular Atrophy
  • Gehrig's Disease
  • Lou Gehrig's Disease
  • Motor System Disease (Focal and Slow)

Disorder Subdivisions

  • Benign Focal Amyotrophy of ALS
  • Infantile Spinal Muscular Atrophy, ALS
  • Juvenile Spinal Muscular Atrophy, Included
  • Kugelberg-Welander Disease
  • Primary Lateral Sclerosis
  • Progressive Bulbar Palsy, Included
  • Spinal Muscular Atrophy, Type ALS
  • Upper Motor Neuron Disease
  • Werdnig-Hoffman Disease
  • Wohlfart-Disease


General Discussion
Amyotrophic lateral sclerosis (ALS) is one of a group of disorders known as motor neuron diseases. It is characterized by the progressive degeneration and eventual death of nerve cells (motor neurons) in the brain, brainstem and spinal cord that facilitate communication between the nervous system and voluntary muscles of the body. Ordinarily, motor neurons in the brain (upper motor neurons) sent messages to motor neurons in the spinal cord (lower motor neurons) and then to various muscles. ALS affects both the upper and lower motor neurons, so that the transmission of messages is interrupted, and muscles gradually weaken and waste away. As a result, the ability to initiate and control voluntary movement is lost. Ultimately, ALS leads to respiratory failure because affected individuals lose the ability to control muscles in the chest and diaphragm. ALS is often called Lou Gehrig?s disease.

Organizations related to Amyotrophic Lateral Sclerosis
  • ALS Society of Canada
    265 Yorkland Blvd
    Ontario Intl M2J 1S5
    Phone #: 416- 49-7 2267
    800 #: 800- 26-7 4257
    e-mail: susan@alsont.ca
    Home page: http://www.alsont.ca
  • Amyotrophic Lateral Sclerosis Association
    27001 Agoura Road
    Calabasas Hills CA 91301-5104
    Phone #: 818-880-9007
    800 #: 800-782-4747
    e-mail: als@alsa-national.org
    Home page: http://www.alsa.org
  • Christopher Reeve Paralysis Foundation
    500 Morris Ave
    Springfield NJ 07081
    Phone #: 973-379-2690
    800 #: 800-225-0292
    e-mail: info@crof.org
    Home page: http://www.crpf.org,
  • Families of Spinal Muscular Atrophy
    P.O. Box 196
    Libertyville IL 60048
    Phone #: 847-367-7620
    800 #: 800-886-1762
    e-mail: sma@fsma.org
    Home page: http://www.curesma.com
  • International Alliance of ALS/MND Associations
    None
    Northampton None NN1 2PR
    Phone #: N/A
    800 #: --
    e-mail: alliance@alsmndalliance.org
    Home page: http://www.alsmndalliance.org/
  • Les Turner Amyotrophic Lateral Sclerosis Foundation, Ltd.
    5550 W. Touhy Avenue, Suite 302
    Skokie IL 60077
    Phone #: 847-679-3311
    800 #: 888-257-1107
    e-mail: info@lesturnerals.org
    Home page: http://www.lesturnerals.org
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Muscular Dystrophy Association
    3300 E. Sunrise Dr
    Tucson AZ 85718
    Phone #: 520-529-2000
    800 #: 800-344-4863
    e-mail: mda@mdausa.org
    Home page: http://www.mdausa.org
  • National Institute of Neurological Disorders and Stroke (NINDS)
    31 Center Drive
    Bethesda MD 20892-2540
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: braininfo@ninds.nih.gov
    Home page: http://www.ninds.nih.gov/
  • New Horizons Un-Limited, Inc.
    811 East Wisconsin Ave
    Milwaukee WI 53202
    Phone #: 414-299-0124
    800 #: N/A
    e-mail: horizons@new-horizons.org
    Home page: http://www.new-horizons.org
  • Scottish Motor Neurone Disease Association
    76 Firhill Rd
    Glasgow Intl G20 7BA
    Phone #: 014-194-51077
    800 #: N/A
    e-mail: info@scotmnd.co.uk
    Home page: http://www.scotmnd.org.uk
  • Spastic Paraplegia Foundation
    11 Douglass Green
    Woburn MA 01801
    Phone #: N/A
    800 #: 877-773-4483
    e-mail: info@sp-foundation.org
    Home page: http://sp-foundation.org
  • Stem Cell Research Foundation
    22512 Gateway Center Drive
    Clarksburg MD 20871
    Phone #: 877-842-3442
    800 #: N/A
    e-mail: info@stemcellresearchfoundation.org
    Home page: http://www.stemcellresearchfoundation.org
  • UCSF Memory and Aging Center
    350 Parnassus Avenue
    San Francisco CA 94117
    Phone #: 415-476-6800
    800 #: N/A
    e-mail: N/A
    Home page: http://memory.ucsf.edu



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html