Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Berylliosis


Synonyms of Berylliosis
  • Acute Beryllium Disease
  • Beryllium Granulomatosis
  • Beryllium Pneumonosis
  • Beryllium Poisoning

Disorder Subdivisions

  • Acute Berylliosis (Acute Beryllium Disease)
  • Chronic Berylliosis (Chronic Beryllium Disease [CBD])


General Discussion
Berylliosis is a form of metal poisoning caused by inhalation of beryllium dusts, vapors, or its compounds or implantation of the substance in the skin. The toxic effects of beryllium most commonly occur due to occupational exposure. Beryllium is a metallic element used in many industries, including electronics, high-technology ceramics, metals extraction, and dental alloy preparation.

There are two forms of beryllium-induced lung disease: acute and chronic. Acute berylliosis has a sudden, rapid onset and is characterized by severe inflammation of the lungs (pneumonitis), coughing, increasing breathlessness (dyspnea), and other associated symptoms and findings. In addition, in some individuals, the skin or the eyes may be affected. The more common, chronic form of the disease develops more slowly and, in some cases, may not become apparent for many years after initial beryllium exposure. Chronic berylliosis is characterized by the abnormal formation of inflammatory masses or nodules (granulomas) within certain tissues and organs and widespread scarring and thickening of deep lung tissues (interstitial pulmonary fibrosis). Although granuloma development primarily affects the lungs, it may also occur within other bodily tissues and organs, such as the skin and underlying (subcutaneous) tissues or the liver. In individuals with chronic berylliosis, associated symptoms and findings often include dry coughing, fatigue, weight loss, chest pain, and increasing shortness of breath.
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Organizations related to Berylliosis
  • American Lung Association
    61 Broadway, 6th Floor
    New York NY 10006
    Phone #: 212-315-8700
    800 #: 800-586-4872
    e-mail: N/A
    Home page: http://www.lungusa.org
  • Centers for Disease Control and Prevention
    1600 Clifton Road NE
    Atlanta GA 30333
    Phone #: 404-639-3534
    800 #: 800-311-3435
    e-mail: http://www.cdc.gov/netinfo.htm
    Home page: http://www.cdc.gov/
  • NIH/National Institute of Allergy and Infectious Diseases
    6610 Rockledge Drive
    Bethesda MD 20892-6612
    Phone #: 301-496-5717
    800 #: --
    e-mail: N/A
    Home page: http://www.niaid.nih.gov/



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html