Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Central Diabetes Insipidus


Synonyms of Central Diabetes Insipidus
  • CDI
  • Neurogenic Diabetes Insipidus
  • Neurohypophyseal Diabetes Insipidus
  • Vasopressin-Sensitive Diabetes Insipidus

Disorder Subdivisions



    General Discussion
    Central diabetes insipidus (CDI) is a rare disorder characterized by excessive thirst (polydipsia) and excessive urination (polyuria). It is not related to the more common diabetes mellitus (sugar diabetes), in which the body does not produce or properly use insulin. CDI is a distinct disorder caused by complete or partial deficiency of the arginine protein, vasopressin (AVP), which is required by the kidneys to manage water balance in the body. If affected individuals do not have access to water, dehydration may occur. Eventually, more serious symptoms can develop including changes in consciousness and confusion associated with dehydration and elevation in serum sodium concentration (hypertonic dehydration). CDI may be caused by any condition that affects the creation, transport or release of vasopressin. CDI may be inherited or acquired. In some cases, no cause can be identified (idiopathic).

    Organizations related to Central Diabetes Insipidus
    • Diabetes Insipidus Foundation, Inc.
      5203 New Prospect Court
      Ellicott City MD 21043
      Phone #: 410-480-0880
      800 #: --
      e-mail: info@diabetesinsipidus.org
      Home page: http://www.diabetesinsipidus.org
    • March of Dimes Birth Defects Foundation
      1275 Mamaroneck Avenue
      White Plains NY 10605
      Phone #: 914-428-7100
      800 #: 888-663-4637
      e-mail: Askus@marchofdimes.com
      Home page: http://www.marchofdimes.com
    • NIH/National Institute of Diabetes, Digestive & Kidney Diseases
      Endocrine Diseases Metabolic Diseases Branch
      Bethesda MD 20892-3570
      Phone #: 301-654-3810
      800 #: --
      e-mail: NDDIC@info.niddk.nih.gov
      Home page: http://www.niddk.nih.gov
    • Pituitary Network Association (PNA)
      P.O. Box 1958
      Thousand Oaks CA 91358
      Phone #: 805-499-9973
      800 #: --
      e-mail: pna@pituitary.org
      Home page: http://www.pituitary.org,



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html