Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Chandler's Syndrome


Synonyms of Chandler's Syndrome
  • Dystrophia Endothelialis Cornea
  • Iris Atrophy with Corneal Edema and Glaucoma

Disorder Subdivisions



    General Discussion
    Chandler's syndrome (CS) is a rare eye disorder in which the single layer of cells lining the interior of the cornea proliferates, causing the drying up of the iris, corneal swelling, and unusually high pressure in the eye (glaucoma). CS is one of three syndromes affecting the eyes (progressive iris atrophy and Cogan-Reese syndrome are the other two) that make up the iridocorneal endothelial syndrome. Chandler?s syndrome affects females more often than males and usually presents sometime during middle age.

    Most often the condition affects one eye only but if it is not treated, with time, the second eye may become involved. The combination of high pressure within the eye (glaucoma) and leaking of fluid through the cellular membrane can result in reduced vision with pain.
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    Organizations related to Chandler's Syndrome
    • NIH/National Eye Institute
      Building 31 Rm 6A32
      Bethesda MD 20892-2510
      Phone #: 301-496-5248
      800 #: --
      e-mail: 2020@nei.nih.gov
      Home page: http://www.nei.nih.gov/
    • National Association for Parents of Children with Visual Impairments (NAPVI)
      P.O. Box 317
      Watertown MA 02472
      Phone #: 617-972-7441
      800 #: 800-562-6265
      e-mail: napvi@perkins.org
      Home page: http://www.napvi.org
    • National Association for Visually Handicapped
      22 West 21st Street
      New York NY 10010
      Phone #: 212-889-3141
      800 #: --
      e-mail: staff@navh.org
      Home page: http://www.navh.org
    • Prevent Blindness America
      211 West Wacker Drive
      Chicago IL 60606
      Phone #: 312-363-6001
      800 #: 800-331-2020
      e-mail: info@preventblindness.org
      Home page: http://www.preventblindness.org
    • Schepens Eye Research Institute
      20 Staniford Street
      Boston MA 02114-2500
      Phone #: 617-912-0100
      800 #: --
      e-mail: geninfo@vision.eri.harvard.edu
      Home page: http://www.theschepens.org/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html