Diseases & Conditions


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Churg Strauss Syndrome


Synonyms of Churg Strauss Syndrome
  • Allergic Angiitis and Granulomatosis
  • Allergic Granulomatosis
  • Allergic Granulomatosis and Angiitis
  • Churg-Strauss Vasculitis
  • Eosinophilic Granulomatous Vasculitis

Disorder Subdivisions



    General Discussion
    Churg-Strauss Syndrome is a rare disorder that may affect multiple organ systems, particularly the lungs. The disorder is characterized by the formation and accumulation of an unusually large number of antibodies, abnormal clustering of certain white blood cells (eosinophilia), inflammation of blood vessels (vasculitis), and the development of inflammatory nodular lesions (granulomatosis).

    Many individuals with Churg-Strauss Syndrome have a history of allergy. In addition, asthma and other associated lung (pulmonary) abnormalities (i.e., pulmonary infiltrates) often precede the development of the generalized (systemic) symptoms and findings seen in Churg-Strauss Syndrome by one or more years. Asthma, a chronic respiratory disorder, is characterized by inflammation and narrowing of the lungs? airways, causing difficulties breathing (dyspnea), coughing, the production of a high-pitched whistling sound while breathing (wheezing), and/or other symptoms and findings.

    Nonspecific findings associated with Churg-Strauss Syndrome typically include flu-like symptoms, such as fever, a general feeling of weakness and fatigue (malaise), loss of appetite (anorexia), weight loss, and muscle pain (myalgia). Additional symptoms and findings may be variable, depending upon the specific organ systems involved. Without appropriate treatment, serious organ damage and potentially life-threatening complications may result.

    Although the exact cause of Churg-Strauss Syndrome is unknown, many researchers indicate that abnormal immunologic and autoimmune factors play an important role.
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    Organizations related to Churg Strauss Syndrome
    • American Lung Association
      61 Broadway, 6th Floor
      New York NY 10006
      Phone #: 212-315-8700
      800 #: 800-586-4872
      e-mail: N/A
      Home page: http://www.lungusa.org
    • American Partnership for Eosinophilic Disorders
      PO Box 29545
      Atlanta GA 30359
      Phone #: 713-493-7749
      800 #: N/A
      e-mail: mail@apfed.org
      Home page: http://www.apfed.org
    • Churg Strauss Syndrome Association
      PO Box 671
      Southampton MA 01073
      Phone #: 413-862-3636
      800 #: N/A
      e-mail: cssa@cssassociation.org
      Home page: http://www.cssassociation.org
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • NIH/National Heart, Lung and Blood Institute Information Center
      P.O. Box 30105
      Bethesda MD 20824-0105
      Phone #: 301-592-8573
      800 #: --
      e-mail: nhlbiinfo@rover.nhlbi.nih.gov
      Home page: N/A
    • NIH/National Institute of Allergy and Infectious Diseases
      6610 Rockledge Drive
      Bethesda MD 20892-6612
      Phone #: 301-496-5717
      800 #: --
      e-mail: N/A
      Home page: http://www.niaid.nih.gov/
    • Vasculitis Foundation
      P.O. Box 28660
      Kansas City MO 64188
      Phone #: 816-436-8211
      800 #: 800-277-9474
      e-mail: vf@vasculitisfoundation.org
      Home page: http://www.vasculitisfoundation.org
    • Vasculitis of the Central Nervous System
      vasculitisoftheCNS@yahoogroups.com
      None None None
      Phone #: 770-978-5636
      800 #: --
      e-mail: SunnyBrook222@aol.com
      Home page: http://www.VasculitisoftheCNS@yahoogroups.com



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html