Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Gorham's Disease


Synonyms of Gorham's Disease
  • Disappearing Bone Disease
  • Essential Osteolysis
  • Gorham's Syndrome
  • Gorham-Stout Syndrome
  • Idiopathic Massive Osteolysis
  • Massive Gorham Osteolysis
  • Massive Osteolysis
  • Morbus Gorham-Stout Disease
  • Progressive Massive Osteolysis
  • Vanishing Bone Disease

Disorder Subdivisions



    General Discussion
    Gorham's disease (GD) is an extremely rare bone disorder; fewer than 200 cases are reported in the medical literature. It is characterized by bone loss (osteolysis) often associated with swelling or abnormal blood vessel growth (angiomatous proliferation). Bone loss can occur in just one bone or spread to soft tissue and adjacent bones.

    Although the disease may strike any of the bones of the body, it is more often recognized earlier when the bones at the top of the head (calvarium) and/or the mandibles are involved.

    Because of its rarity, the disorder often goes unrecognized. As a result of that, coupled with a lack of agreement on how best to treat Gorham?s disease once it is recognized, treatment may often be delayed. The cause of Gorham?s disease is unknown.

    Organizations related to Gorham's Disease
    • Lymphangiomatosis & Gorham's Disease Alliance
      19919 Villa Lante Place
      Boca Raton FL 33434
      Phone #: 561-441-9766
      800 #: N/A
      e-mail: info@lgdalliance.org
      Home page: http://www.lgdalliance.org/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
      1 AMS Circle
      Bethesda MD 20892-3675
      Phone #: 301-495-4484
      800 #: 877-226-4267
      e-mail: NIAMSinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html