Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Hemophilia


Synonyms of Hemophilia
  • AHF Deficiency
  • AHG Deficiency
  • Antihemophilic Factor Deficiency
  • Antihemophilic Globulin Deficiency
  • Christmas Disease
  • Classical Hemophilia

Disorder Subdivisions

  • Hemophilia A (Factor VIII Deficiency)
  • Hemophilia B (Factor IX Deficiency)
  • Hemophilia C (Factor XI Deficiency)


General Discussion
Hemophilia is a rare inherited blood clotting (coagulation) disorder caused by inactive or deficient blood proteins (usually factor VIII). Factor VIII is one of several proteins that enable the blood to clot. Hemophilia may be classified as mild, moderate, or severe. The level of severity is determined by the percentage of active clotting factor in the blood (normal percentage ranges from 50 to 150 percent). People who have severe hemophilia have less than one percent of active clotting factor in their blood.

There are three major types of hemophilia: hemophilia A (also known as classical hemophilia, factor VIII deficiency or antihemophilic globulin [AHG] deficiency); hemophilia B (Christmas disease or factor IX deficiency); and hemophilia C (factor XI deficiency). Hemophilia A and B are inherited as X-linked recessive genetic traits, while Hemophilia C is inherited as an autosomal recessive genetic trait. Therefore, while hemophilia A and B are fully expressed in males only, hemophilia C affects males and females in equal numbers.

Organizations related to Hemophilia
  • Canadian Hemophilia Society
    625 President Kennedy
    Quebec None H3A 1K2
    Phone #: 514-848-0503
    800 #: 800-668-2686
    e-mail: chs@hemophilia.ca
    Home page: http://www.hemophilia.ca
  • Cochrane Cystic Fibrosis and Genetic Disorders Review Group
    Institute of Child Health
    Liverpool None L12 2 AP
    Phone #: +44- (0-) 1512525696
    800 #: --
    e-mail: cfgd@liv.ac.uk
    Home page: http://www.liv.ac.uk/cfgd/
  • Hemophilia Federation of America
    1405 West Pinhook Road
    Lafayette LA 70503
    Phone #: 337-261-9787
    800 #: 800-203-9797
    e-mail: s.swindle@cox-internet.com
    Home page: http://www.hemophiliafed.org
  • Irish Haemophilia Society
    Iceland House
    Dublin None 7
    Phone #: 01 -872-4466
    800 #: N/A
    e-mail: haemophiliasociety@eircom.net
    Home page: http://www.haemophilia-society.ie
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • March of Dimes Birth Defects Foundation
    1275 Mamaroneck Avenue
    White Plains NY 10605
    Phone #: 914-428-7100
    800 #: 888-663-4637
    e-mail: Askus@marchofdimes.com
    Home page: http://www.marchofdimes.com
  • NIH/National Heart, Lung and Blood Institute Information Center
    P.O. Box 30105
    Bethesda MD 20824-0105
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: N/A
  • National Hemophilia Foundation
    116 West 32nd Street
    New York NY 10001
    Phone #: 212-328-3737
    800 #: 800-424-2634
    e-mail: gwidlundDhemophilia.org
    Home page: http://www.hemophilia.org
  • Sj?ldne Diagnoser / Rare Disorders Denmark
    Frederiksholms Kanal 2, 3rd Floor
    Copenhagen K None 1220
    Phone #: 45 -33 -14 00 10
    800 #: N/A
    e-mail: mail@sjaeldnediagnoser
    Home page: http://www.raredisorders.dk
  • World Federation of Hemophilia
    1425 Rene Levesque Boulevard West
    Quebec Intl H3G 1T7
    Phone #: 514--87-5-7944
    800 #: --
    e-mail: wfh@wfh.org
    Home page: http://www.wfh.org



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html