Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Hemophilia B


Synonyms of Hemophilia B
  • Christmas Disease
  • Factor IX Deficiency

Disorder Subdivisions



    General Discussion
    Hemophilia B is a rare genetic bleeding disorder in which affected individuals have insufficient levels of a blood protein called factor IX. Factor IX is a clotting factor. Clotting factors are specialized proteins that are essential for clotting, the process by which blood clumps together to plug the site of a wound to stop bleeding. Individuals with hemophilia B do not bleed faster or more profusely than healthy individuals, but, because their blood clots poorly, they have difficulty stopping the flow of blood from a wound. This may be referred to as prolonged bleeding or a prolonged bleeding episode. Hemophilia B can be mild, moderate or severe. In mild cases, prolonged bleeding episodes may only occur after surgery or dental procedures. In more severely affected individuals, symptoms may include prolonged bleeding from minor wounds, painful swollen bruises, and unexplained (spontaneous) bleeding into vital organs as well as joints and muscles . Hemophilia B is caused by disruptions or changes (mutations) to the F9 gene on the X chromosome. The disorder is almost always fully expressed in males only, although some females who carry the gene may have mild or ,rarely, severe symptoms of bleeding. Hemophilia B is also known as factor IX deficiency or Christmas disease.

    Organizations related to Hemophilia B
    • Canadian Hemophilia Society
      625 President Kennedy
      Quebec None H3A 1K2
      Phone #: 514-848-0503
      800 #: 800-668-2686
      e-mail: chs@hemophilia.ca
      Home page: http://www.hemophilia.ca
    • Hemophilia Federation of America
      1405 West Pinhook Road
      Lafayette LA 70503
      Phone #: 337-261-9787
      800 #: 800-203-9797
      e-mail: s.swindle@cox-internet.com
      Home page: http://www.hemophiliafed.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • NIH/National Heart, Lung and Blood Institute Information Center
      P.O. Box 30105
      Bethesda MD 20824-0105
      Phone #: 301-592-8573
      800 #: --
      e-mail: nhlbiinfo@rover.nhlbi.nih.gov
      Home page: N/A
    • National Hemophilia Foundation
      116 West 32nd Street
      New York NY 10001
      Phone #: 212-328-3737
      800 #: 800-424-2634
      e-mail: gwidlundDhemophilia.org
      Home page: http://www.hemophilia.org
    • World Federation of Hemophilia
      1425 Rene Levesque Boulevard West
      Quebec Intl H3G 1T7
      Phone #: 514--87-5-7944
      800 #: --
      e-mail: wfh@wfh.org
      Home page: http://www.wfh.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html