Diseases & Conditions


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Human Granulocytic Ehrlichiosis (HGE)


Synonyms of Human Granulocytic Ehrlichiosis (HGE)
  • HGE
  • Human Ehrlichial Infection, Human Granulocytic Type

Disorder Subdivisions



    General Discussion
    Human Granulocytic Ehrlichiosis (HGE) is a rare infectious disease that belongs to a group of diseases known as the Human Ehrlichioses. The Ehrlichioses are infectious diseases caused by bacteria in the Ehrlichia family. Several forms of Human Ehrlichial infection have been identified including Human Granulocytic Ehrlichiosis (HGE), Sennetsu Fever, and Human Monocytic Ehrlichiosis (HME). Though caused by different strains of Ehrlichia bacteria, the disorders are all characterized by similar symptoms.

    The symptoms of Human Granulocytic Ehrlichiosis (HGE) may include a sudden high fever, headache, muscle aches (myalgia), chills, and a general feeling of weakness and fatigue (malaise) within a week or so after initial infection. In most cases, abnormal laboratory findings may occur including an abnormally low number of circulating blood platelets (thrombocytopenia), a decrease in white blood cells (leukopenia), and an abnormal increase in the level of certain liver enzymes (hepatic transaminases). In some cases, symptoms may progress to include nausea, vomiting, cough, diarrhea, loss of appetite (anorexia), and/or confusion. If Human Granulocytic Ehrlichiosis is left untreated, life-threatening symptoms, such as kidney failure and/or respiratory problems, may develop in some cases. Human Granulocytic Ehrlichiosis is caused by a bacterium of the Ehrlichiosis family that has not yet been named. The Ehrlichial bacterium is carried and transmitted by certain ticks (vectors), such as the deer tick (Ixodes dammini) and the American dog tick (Dermacentor variabilis).

    Organizations related to Human Granulocytic Ehrlichiosis (HGE)
    • American Lyme Disease Foundation, Inc.
      PO Box 684
      Somers NY 10589
      Phone #: N/A
      800 #: N/A
      e-mail: inquire@aldf.com
      Home page: http://www.aldf.com
    • Centers for Disease Control and Prevention
      1600 Clifton Road NE
      Atlanta GA 30333
      Phone #: 404-639-3534
      800 #: 800-311-3435
      e-mail: http://www.cdc.gov/netinfo.htm
      Home page: http://www.cdc.gov/
    • Lyme Disease Foundation
      P.O. Box 332
      Tolland CT 06084
      Phone #: 860-525-2000
      800 #: 800-886-5963
      e-mail: lymefnd@aol.com
      Home page: http://www.lyme.org
    • NIH/National Institute of Allergy and Infectious Diseases
      6610 Rockledge Drive
      Bethesda MD 20892-6612
      Phone #: 301-496-5717
      800 #: --
      e-mail: N/A
      Home page: http://www.niaid.nih.gov/
    • World Health Organization (WHO) Regional Office for the Americas (AMRO)
      Pan American Health Organization (PAHO)
      Washington DC 20037
      Phone #: 202-974-3000
      800 #: --
      e-mail: postmaster@paho.org
      Home page: http://www.who.ch/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html