Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Leukodystrophy


Synonyms of Leukodystrophy

    Disorder Subdivisions

    • Alexander Disease
    • Canavan Disease
    • Cerebrotendinous Xanthomatosis
    • Childhood Ataxia and Cerebral Hypomyelination (CACH)
    • Krabbe Disease
    • Megalencephaly with Subcortical Cysts
    • Metachromatic Leukodystrophy
    • Multiple Sulfatase Deficiency
    • Other Leukodystrophies
    • Pelizaeus-Merzbacher Disease
    • Refsum Disease
    • X-linked Adrenoleukodystrophy
    • Zellweger Syndrome Spectrum Disorders


    General Discussion
    Leukodystrophies are a group of very rare, progressive, metabolic, genetic diseases that affect the brain, spinal cord and often the peripheral nerves. Each type of leukodystrophy is caused by a specific gene abnormality that leads to abnormal development of one of at least 10 different chemicals that make up the white matter (myelin sheath) of the brain. The myelin sheath is the protective covering of the nerve and nerves can?t function normally with out it. Each type of leukodystrophy affects a different part of the myelin sheath, leading to a range of neurological problems.

    Organizations related to Leukodystrophy
    • Australian Leukodystrophy Support Group, Inc.
      10 Mitchell Street
      Mentone, Victoria None 3194
      Phone #: 001-1(0-3)9584 7070
      800 #: N/A
      e-mail: leuko@vicnet.net.au
      Home page: http://www.alds.org.au
    • Hunter's Hope Foundation, Inc.
      PO Box 643
      Orchard Park NY 14127
      Phone #: 716-667-1200
      800 #: 877-984-4673
      e-mail: info@huntershope.org
      Home page: http://www.huntershope.org
    • Kennedy Krieger Institute
      707 North Broadway
      Baltimore MD 21205
      Phone #: 443-923-9200
      800 #: 800-873-3377
      e-mail: webmaster@kennedykrieger.org
      Home page: http://www.kennedykrieger.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • National Institute of Neurological Disorders and Stroke (NINDS)
      31 Center Drive
      Bethesda MD 20892-2540
      Phone #: 301-496-5751
      800 #: 800-352-9424
      e-mail: braininfo@ninds.nih.gov
      Home page: http://www.ninds.nih.gov/
    • National Tay-Sachs and Allied Diseases Association, Inc.
      2001 Beacon Street
      Brighton MA 02135
      Phone #: 617-277-4463
      800 #: 800-906-8723
      e-mail: info@ntsad.org
      Home page: http://www.NTSAD.org
    • United Leukodystrophy Foundation
      2304 Highland Drive
      Sycamore IL 60178
      Phone #: 815-895-3211
      800 #: 800-728-5483
      e-mail: office@ulf.org
      Home page: http://www.ulf.org/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html