Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Muscular Dystrophy, Oculopharyngeal


Synonyms of Muscular Dystrophy, Oculopharyngeal
  • Autosomal Dominant OPMD
  • Autosomal Recessive OPMD
  • Muscular dystrophy, Oculopharyngeal
  • OPMD

Disorder Subdivisions



    General Discussion
    Oculopharyngeal muscular dystrophy (OPMD) is a rare genetic muscle disorder with onset during adulthood most often between 40 and 60 years of age. OPMD is characterized by slowly progressive muscle disease (myopathy) affecting the muscles of the upper eyelids and the throat. Affected individuals may develop drooping of the eyelids (ptosis), double vision (diplopia) and/or difficulty swallowing (dysphagia). Eventually, additional muscles may become involved including those of the upper legs and arms (proximal limb weakness). In some cases, muscle weakness of the legs may eventually cause difficulty walking. OPMD may be inherited as an autosomal dominant or recessive trait.

    OPMD belongs to a group of rare genetic muscle disorders known as the muscular dystrophies. These disorders are characterized by weakness and atrophy of various voluntary muscles of the body. Approximately 30 different disorders make up the muscular dystrophies. The disorders affect different muscles and have different ages of onset, severity and inheritance patterns. Unlike OPMD, most forms of muscular dystrophy have onset during childhood or adolescence.

    Organizations related to Muscular Dystrophy, Oculopharyngeal
    • European Alliance of Neuromuscular Disorders Associations
      MDG Malta 4,
      Gzira Intl GAR 04
      Phone #: 003-56 -21 346688
      800 #: --
      e-mail: eamda@hotmail.com
      Home page: http://www.eamda.net
    • March of Dimes Birth Defects Foundation
      1275 Mamaroneck Avenue
      White Plains NY 10605
      Phone #: 914-428-7100
      800 #: 888-663-4637
      e-mail: Askus@marchofdimes.com
      Home page: http://www.marchofdimes.com
    • Muscular Dystrophy Association
      3300 E. Sunrise Dr
      Tucson AZ 85718
      Phone #: 520-529-2000
      800 #: 800-344-4863
      e-mail: mda@mdausa.org
      Home page: http://www.mdausa.org
    • Muscular Dystrophy Campaign
      7-11 Prescott Place
      London None SW4 6BS
      Phone #: N/A
      800 #: --
      e-mail: info@muscular-dystrophy.org
      Home page: http://www.muscular-dystrophy.org
    • National Institute of Neurological Disorders and Stroke (NINDS)
      31 Center Drive
      Bethesda MD 20892-2540
      Phone #: 301-496-5751
      800 #: 800-352-9424
      e-mail: braininfo@ninds.nih.gov
      Home page: http://www.ninds.nih.gov/
    • Society for Muscular Dystrophy Information International
      P.O. Box 4790
      Nova Scotia None B4V 2X6
      Phone #: 902--68-5-3961
      800 #: --
      e-mail: smdi@auracom.com
      Home page: http://users.auracom.com/smdi



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html