Neutropenia, General / Disease

Diseases & Conditions

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Neutropenia, General

Synonyms of Neutropenia, General

Neutropenia, Autoimmune

Disorder Subdivisions

Neutropenia, Chronic Congenital
Neutropenia, Chronic Idiopathic
Neutropenia, Cyclic

General Discussion
Severe chronic neutropenia (SCN) is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the body (neutropenia). Neutrophils play an essential role in fighting bacterial infections by surrounding and destroying invading bacteria (phagocytosis). Symptoms associated with severe chronic neutropenia include recurring fevers, mouth sores (ulcers), and/or inflammation of the tissues that surround and support the teeth (periodontitis). Due to low levels of neutrophils, affected individuals may be more susceptible to recurring infections that, in some cases, may result in life-threatening complications. SCN may last for months or years and can affect both children and adults. Clinicians recognize four forms of the disorder: congenital, cyclical, idiopathic, and autoimmune neutropenia. The term idiopathic is used when severe chronic neutropenia occurs for unknown reasons.

Organizations related to Neutropenia, General

MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay WI 54301-1243
Phone #: 920-336-5333
800 #: 877-336-5333
e-mail: mums@netnet.net
Home page: http://www.netnet.net/mums/
NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda MD 20824-0105
Phone #: 301-592-8573
800 #: --
e-mail: nhlbiinfo@rover.nhlbi.nih.gov
Home page: N/A
National Neutropenia Network
PO Box 1693
Brighton MI 48116
Phone #: 810-229-5797
800 #: N/A
e-mail: leereeves99@gmail.com
Home page: http://www.neutropenianet.org
Neutropenia Support Association, Inc.
971 Corydon Avenue
Manitoba None R3M 3S7
Phone #: 204-489-8454
800 #: 800-663-8876
e-mail: stevensl@neutropenia.ca
Home page: http://www.neutropenia.ca
Severe Chronic Neutropenia International Registry
Plaza 600 Building
Seattle WA 98101
Phone #: 206-543-9749
800 #: 800-726-4463
e-mail: Registry@u.washington.edu
Home page: http://www.depts.washington.edu/registry/
Severe Chronic Neutropenia International Registry Australia
2nd Floor Marian House
Ballarat None 3350
Phone #: 61--3-5-333 4811
800 #: --
e-mail: scnirau@ballarat.edu.au
Home page: http://www.freyja.ballarat.edu.au:8080/~scnirau/

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html