Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Neutropenia, General


Synonyms of Neutropenia, General
  • Neutropenia, Autoimmune

Disorder Subdivisions

  • Neutropenia, Chronic Congenital
  • Neutropenia, Chronic Idiopathic
  • Neutropenia, Cyclic


General Discussion
Severe chronic neutropenia (SCN) is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the body (neutropenia). Neutrophils play an essential role in fighting bacterial infections by surrounding and destroying invading bacteria (phagocytosis). Symptoms associated with severe chronic neutropenia include recurring fevers, mouth sores (ulcers), and/or inflammation of the tissues that surround and support the teeth (periodontitis). Due to low levels of neutrophils, affected individuals may be more susceptible to recurring infections that, in some cases, may result in life-threatening complications. SCN may last for months or years and can affect both children and adults. Clinicians recognize four forms of the disorder: congenital, cyclical, idiopathic, and autoimmune neutropenia. The term idiopathic is used when severe chronic neutropenia occurs for unknown reasons.

Organizations related to Neutropenia, General
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • NIH/National Heart, Lung and Blood Institute Information Center
    P.O. Box 30105
    Bethesda MD 20824-0105
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: N/A
  • National Neutropenia Network
    PO Box 1693
    Brighton MI 48116
    Phone #: 810-229-5797
    800 #: N/A
    e-mail: leereeves99@gmail.com
    Home page: http://www.neutropenianet.org
  • Neutropenia Support Association, Inc.
    971 Corydon Avenue
    Manitoba None R3M 3S7
    Phone #: 204-489-8454
    800 #: 800-663-8876
    e-mail: stevensl@neutropenia.ca
    Home page: http://www.neutropenia.ca
  • Severe Chronic Neutropenia International Registry
    Plaza 600 Building
    Seattle WA 98101
    Phone #: 206-543-9749
    800 #: 800-726-4463
    e-mail: Registry@u.washington.edu
    Home page: http://www.depts.washington.edu/registry/
  • Severe Chronic Neutropenia International Registry Australia
    2nd Floor Marian House
    Ballarat None 3350
    Phone #: 61--3-5-333 4811
    800 #: --
    e-mail: scnirau@ballarat.edu.au
    Home page: http://www.freyja.ballarat.edu.au:8080/~scnirau/



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html