Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Orocraniodigital Syndrome


Synonyms of Orocraniodigital Syndrome
  • Cleft Lip/Palate with Abnormal Thumbs and Microcephaly
  • Cranio-Oro-Digital Syndrome
  • Digital-Oro-Cranio Syndrome
  • Juberg Hayward Syndrome

Disorder Subdivisions



    General Discussion
    Orocraniodigital syndrome is an extremely rare inherited disorder characterized by multiple malformations of the head and face (craniofacial area) and the fingers and toes (digits). Major characteristics may include a vertical groove in the upper lip (cleft lip) and/or the inside, upper portion of the mouth (cleft palate), an abnormally small head (microcephaly), widely spaced eyes (ocular hypertelorism), improper development (hypoplasia) of the thumbs and/or toes, and/or webbing (syndactyly) of the toes. In some cases, malformations of certain skeletal bones may also be present. Mental retardation has occurred in the majority of cases. Orocraniodigital syndrome may be inherited as an autosomal recessive genetic trait.

    Organizations related to Orocraniodigital Syndrome
    • AmeriFace
      PO Box 751112
      Las Vegas NV 89136
      Phone #: 702-769-9264
      800 #: 888-486-1209
      e-mail: info@ameriface.org
      Home page: http://www.ameriface.org
    • Children's Craniofacial Association
      13140 Coit Road
      Dallas TX 75240
      Phone #: 214-570-9099
      800 #: 800-535-3643
      e-mail: csmith@ccakids.com
      Home page: http://www.ccakids.com
    • Cleft Palate Foundation
      1504 East Franklin Street
      Chapel Hill NC 27514-2820
      Phone #: 919-933-9044
      800 #: 800-242-5338
      e-mail: info@cleftline.org
      Home page: http://www.cleftline.org
    • FACES: The National Craniofacial Association
      P.O. Box 11082
      Chattanooga TN 37401
      Phone #: 423-266-1632
      800 #: 800-332-2373
      e-mail: faces@faces-cranio.org
      Home page: http://www.faces-cranio.org
    • Forward Face, Inc.
      317 East 34th Street
      New York NY 10016
      Phone #: 212-684-5860
      800 #: 800-393-3223
      e-mail: info@forwardface.org
      Home page: http://www.forwardface.org
    • National Craniofacial Foundation
      3100 Carlisle Street
      Dallas TX 75204
      Phone #: --
      800 #: 800-535-3643
      e-mail: N/A
      Home page: N/A
    • Wide Smiles
      P.O. Box 5153
      Stockton CA 95205-0153
      Phone #: 209-942-2812
      800 #: --
      e-mail: JoSmiles@yahoo.com
      Home page: http://www.widesmiles.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html