Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Polymorphous Low-Grade Adenocarcinoma


Synonyms of Polymorphous Low-Grade Adenocarcinoma
  • Lobular Carcinoma of the Minor Salivary Glands
  • Low-Grade Papillary Carcinoma of the Palate
  • Pleomorphic Adenoma
  • PLGA
  • Terminal Duct Carcinoma

Disorder Subdivisions



    General Discussion
    Polymorphous low-grade adenocarcinoma (PLGA) is a rare tumor of the salivary glands that is limited, to a great extent, to the minor salivary glands and commonly, but not exclusively, localized in the palate of the mouth. The major salivary glands are the parotid glands (at the side of the face, below the ears), the sublingual glands (below the tongue), and the submandibular glands (below the lower jaw). As the name suggests, each of the major salivary glands is of substantial size and visible to the naked eye. There are about 600 to 1,000 minor salivary glands that are microscopic in size. These minor salivary glands are found in the lining (mucosa) of the lips, tongue, and hard and soft palate, as well as inside the nose, cheeks, and sinuses.

    Less than one (1%) per cent of all cancers reported in the USA are salivary cancers and, of these, 80% begin in the parotid glands, and about 15% begin in the submandibular glands, leaving only 5% that begin in the sublingual and minor salivary glands. Most of the tumors that start in the major salivary glands turn out to be benign, while most, but not all, of the cancers that start in the minor salivary glands turn out to be malignant.

    Organizations related to Polymorphous Low-Grade Adenocarcinoma
    • American Cancer Society, Inc.
      1599 Clifton Road NE
      Atlanta GA 30329
      Phone #: 404-320-3333
      800 #: 800-227-2345
      e-mail: N/A
      Home page: http://www.cancer.org
    • Friends of Cancer Research
      2231 Crystal Drive
      Arlington VA 22202
      Phone #: 703-302-1503
      800 #: N/A
      e-mail: info@focr.org
      Home page: http://www.focr.org
    • Lance Armstrong Foundation
      PO Box 161550
      Austin TX 78716-1150
      Phone #: 512-236-8820
      800 #: 866-235-7205
      e-mail: N/A
      Home page: http://www.livestrong.org
    • Let's Face It (USA)
      P.O. Box 29972
      Bellingham WA 98228-1972
      Phone #: 360-676-7325
      800 #: --
      e-mail: faceit@umich.edu
      Home page: http://www.dent.umich.edu/faceit
    • National Cancer Institute
      6116 Executive Blvd, MSC 8322, Room 3036A
      Bethesda MD 20892-8322
      Phone #: 301-435-3848
      800 #: 800-422-6237
      e-mail: N/A
      Home page: http://www.cancer.gov
    • Support for People with Oral and Head and Neck Cancer, Inc.
      P.O. Box 53
      Locust Valley NY 11560-0053
      Phone #: 516-759-5333
      800 #: --
      e-mail: info@spohnc.org
      Home page: http://www.spohnc.org
    • Wellness Community
      919 18th Street N.W.
      Washington DC 20006
      Phone #: 202-659-9709
      800 #: 888-793-9355
      e-mail: help@thewellnesscommunity.org
      Home page: http://www.thewellnesscommunity.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html