Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Pseudoxanthoma Elasticum (PXE)


Synonyms of Pseudoxanthoma Elasticum (PXE)
  • elastosis dystrophica syndrome (obsolete)
  • Gronblad-Strandberg syndrome
  • systemic elastorrhexis (obsolete)

Disorder Subdivisions

  • PXE, dominant type
  • PXE, recessive type


General Discussion
Pseudoxanthoma elasticum, PXE, is an inherited disorder that affects selected connective tissue in some parts of the body. Elastic tissue in the body becomes mineralized; that is, calcium and other minerals are deposited in the tissue. This can result in changes in the skin, eyes, cardiovascular system, and gastrointestinal system. Clinicians first recognized PXE more than 100 years ago. Researchers have made a number of significant advances in the past few years.

Organizations related to Pseudoxanthoma Elasticum (PXE)
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Macular Degeneration Support, Inc.
    3600 Blue Ridge
    Grandview MO 64030
    Phone #: 816-761-7080
    800 #: N/A
    e-mail: director@mdsupport.org
    Home page: http://www.mdsupport.org
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
    1 AMS Circle
    Bethesda MD 20892-3675
    Phone #: 301-495-4484
    800 #: 877-226-4267
    e-mail: NIAMSinfo@mail.nih.gov
    Home page: http://www.niams.nih.gov/Health_Info
  • NIH/National Eye Institute
    Building 31 Rm 6A32
    Bethesda MD 20892-2510
    Phone #: 301-496-5248
    800 #: --
    e-mail: 2020@nei.nih.gov
    Home page: http://www.nei.nih.gov/
  • NIH/National Heart, Lung and Blood Institute Information Center
    P.O. Box 30105
    Bethesda MD 20824-0105
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: N/A
  • National Association for Pseudoxanthoma Elasticum (NAPE)
    8764 Manchester Road
    St Louis MO 63144-2724
    Phone #: 314-962-0100
    800 #: --
    e-mail: napestlouis@sbcglobal.net
    Home page: http://www.napxe.org
  • PXE International, Inc.
    4301 Connecticut Ave NW
    Washington DC 20008-2304
    Phone #: 202-362-9599
    800 #: --
    e-mail: pxe@pxe.org
    Home page: http://www.pxe.org



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html