Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Restless Legs Syndrome


Synonyms of Restless Legs Syndrome
  • Ekbom Syndrome

Disorder Subdivisions



    General Discussion
    Restless legs syndrome (RLS) is a neurologic and sleep related movement disorder characterized by an irresistible urge to move in the legs that typically occurs or worsens at rest. It is usually accompanied by abnormal, uncomfortable sensations, known as paresthesias or dysesthesias, that are often likened to crawling, cramping, aching, burning, itching, or prickling deep within the affected areas. Although the legs are usually involved, an urge to move with paresthesias or dysesthesias may also sometimes affect the arms or other areas of the body. Those with RLS may vigorously move the affected area, engage in pacing, or perform other, often repetitive movements, such as stretching, bending, or rocking. Symptoms typically worsen in the evening or at night, often resulting in sleep disturbances. Some individuals with RLS may also develop symptoms during other extended periods of inactivity, such as while sitting in a movie theater or traveling in a car.

    RLS may occur as a primary condition or due to another underlying disorder, certain medications, or other factors (secondary or symptomatic RLS). In primary RLS, the disorder is often genetic in origin or occurs for unknown reasons (idiopathic). Secondary RLS may occur in association with certain conditions, such as iron deficiency, low levels of the oxygen-carrying component of red blood cells (anemia), kidney failure, or pregnancy.

    Organizations related to Restless Legs Syndrome
    • March of Dimes Birth Defects Foundation
      1275 Mamaroneck Avenue
      White Plains NY 10605
      Phone #: 914-428-7100
      800 #: 888-663-4637
      e-mail: Askus@marchofdimes.com
      Home page: http://www.marchofdimes.com
    • National Institute of Neurological Disorders and Stroke (NINDS)
      31 Center Drive
      Bethesda MD 20892-2540
      Phone #: 301-496-5751
      800 #: 800-352-9424
      e-mail: braininfo@ninds.nih.gov
      Home page: http://www.ninds.nih.gov/
    • National Sleep Foundation
      1522 K Street
      Washington D.C. 20005
      Phone #: 202-347-3471
      800 #: --
      e-mail: nsf@sleepfoundation.org
      Home page: http://www.sleepfoundation.org
    • Restless Legs Syndrome Foundation, Inc.
      819 Second St SW
      Rochester MN 55902
      Phone #: 507-287-6465
      800 #: 877-463-6757
      e-mail: rlsfoundation@rls.org
      Home page: http://www.rls.org
    • WE MOVE (Worldwide Education and Awareness for Movement Disorders)
      204 West 84th Street
      New York NY 10024
      Phone #: 212-875-8312
      800 #: N/A
      e-mail: wemove@wemove.org
      Home page: http://www.wemove.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html