Diseases & Conditions


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Urticaria, Cholinergic


Synonyms of Urticaria, Cholinergic
  • Physical Urticaria, Cholinergic Type

Disorder Subdivisions



    General Discussion
    Cholinergic urticaria is a relatively common disorder of the immune system characterized by an immediate skin reaction (hypersensitivity) to heat, emotional stress, and/or exercise. Symptoms of the disorder include the appearance of distinctive small skin eruptions (hives) with well-defined borders and pale centers, surrounded by patches of red skin (wheal-and-flare reaction). These red areas are typically intensely itchy (pruritus). Occasionally, cholinergic urticaria may be associated with systemic symptoms such as fever and/or difficulty breathing.

    The symptoms of cholinergic urticaria may develop due to the reaction of specific immune system antibodies (IgE) to certain antigens, leading to a hypersensitivity response (Type I) and the wheal-and-flare reaction that is typical of cholinergic urticaria.

    Organizations related to Urticaria, Cholinergic
    • American Academy of Allergy, Asthma and Immunology
      611 East Wells Street
      Milwaukee WI 53202
      Phone #: 414-272-6071
      800 #: 800-822-2762
      e-mail: info@aaaai.org
      Home page: http://www.aaaai.org
    • NIH/National Institute of Allergy and Infectious Diseases
      6610 Rockledge Drive
      Bethesda MD 20892-6612
      Phone #: 301-496-5717
      800 #: --
      e-mail: N/A
      Home page: http://www.niaid.nih.gov/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html