Adams Oliver Syndrome / Disease

Diseases & Conditions

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Adams Oliver Syndrome

Synonyms of Adams Oliver Syndrome

Absence Defect of Limbs, Scalp and Skull
Aplasia Cutis Congenita with Terminal Transverse Limb Defects
Congenital Scalp Defects with Distal Limb Reduction Anomalies

Disorder Subdivisions

General Discussion
Adams-Oliver syndrome (AOS) is an extremely rare inherited disorder characterized by defects of the scalp and abnormalities of the fingers, toes, arms, and/or legs. The physical abnormalities associated with this disorder vary greatly among affected individuals. Some cases may be very mild while others may be severe. In infants with Adams-Oliver syndrome, scalp defects are present at birth (congenital) and may include one or multiple hairless scarred areas that may have abnormally wide (dilated) blood vessels directly under the affected skin. In severe cases, an underlying defect of the bones of the skull may also be present. In addition, infants with this disorder typically have malformations of the hands, arms, feet, and/or legs. These range from abnormally short (hypoplastic) fingers and toes to absent hands and/or lower legs. In some cases, additional abnormalities may also be present. Most cases of AOS appear to follow autosomal dominant inheritance but autosomal recessive inheritance has also been reported.

Organizations related to Adams Oliver Syndrome

AOSupport
None
None None None
Phone #: N/A
800 #: N/A
e-mail: N/A
Home page: http://www.aosupport.org
Adams Oliver Syndrome Support Group
14 College View
Deeside Intl CH5 4BY
Phone #: 012-44 -816209
800 #: --
e-mail: [email protected]
Home page: N/A
Birth Defect Research for Children
930 Woodcock Rd
Orlando FL 32803
Phone #: 407-895-0802
800 #: --
e-mail: [email protected]
Home page: http://www.birthdefects.org
NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
1 AMS Circle
Bethesda MD 20892-3675
Phone #: 301-495-4484
800 #: 877-226-4267
e-mail: [email protected]
Home page: http://www.niams.nih.gov/Health_Info

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html