Diseases & Conditions


Adenoid Cystic Carcinoma

Synonyms of Adenoid Cystic Carcinoma
  • ACC
  • Adenocystic Carcinoma
  • Cribriform Carcinoma
  • Cylindroma

Disorder Subdivisions

    General Discussion
    This disease entry was made possible due to the generosity of the Kathleen Keany Memorial Foundation, 8502 East Chapman Avenue, Suite 195, Orange, CA 92869, (714) 538-6920.

    Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer that most commonly develops in the salivary glands or other regions of the head and neck. In some cases, ACC may arise in other primary sites, such as the skin; the breast; the neck of the uterus (cervix) in females; the prostate gland in males; or other areas.

    The term cancer refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread (metastasize) to distant bodily tissues or organs via the bloodstream, the lymphatic system, or other means. Different forms of cancer, including adenoid cystic carcinoma, may be classified based upon the cell type involved, the specific nature of the malignancy, the tissues or organs affected, and the disease's clinical course.

    ACC tumors are characterized by a distinctive pattern in which abnormal nests or cords of certain cells (epithelial cells) surround and/or infiltrate ducts or glandular structures within the affected organ. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes (hyaline membranes). Such characteristics are apparent during microscopic evaluation of the tumor cells. ACC is considered a low-grade malignancy that has a history of slow growth, but tends to be aggressively invasive and to infiltrate nearby lymph nodes as well as the sheaths or coatings surrounding nerve fibers (perineural spaces). This form of cancer may have a tendency to recur later at the site where it first developed (local recurrence) and to spread to distant bodily sites, particularly the lungs, potentially resulting in life-threatening complications.

    Organizations related to Adenoid Cystic Carcinoma
    • Adenoid Cystic Carcinoma Alliance
      PO Box 82
      Green Valley AZ 85614
      Phone #: 520-625-5495
      800 #: --
      e-mail: [email protected]
      Home page: http://www.rare-cancer.org/adenoid-cystic-carcinoma/
    • Adenoid Cystic Carcinoma Organization International
      5605 77th Street East
      Puyallup WA 98371
      Phone #: --
      800 #: --
      e-mail: [email protected]
      Home page: http://www.orgsites.com/ca/acco
    • Adenoid Cystic Carcinoma Research Foundation
      P.O. Box 442
      Needham MA 02494
      Phone #: 781-248-9699
      800 #: N/A
      e-mail: [email protected]
      Home page: http://www.accrf.org
    • American Cancer Society, Inc.
      1599 Clifton Road NE
      Atlanta GA 30329
      Phone #: 404-320-3333
      800 #: 800-227-2345
      e-mail: N/A
      Home page: http://www.cancer.org
    • Association of Community Cancer Centers
      11600 Nebel Street
      Rockville MD 20852
      Phone #: 301-984-9496
      800 #: --
      e-mail: N/A
      Home page: http://www.accc-cancer.org
    • Canadian Cancer Society
      10 Alcorn Avenue
      Toronto None M4V 3B1
      Phone #: (41-6) -961-7223
      800 #: (88-8) -939-3333
      e-mail: [email protected]
      Home page: http://www.cancer.ca/
    • Cancer Hope Network
      2 North Road
      Chester NJ 07930
      Phone #: 908-879-4039
      800 #: 877-467-3638
      e-mail: [email protected]
      Home page: http://www.cancerhopenetwork.org
    • Cancer.Net
      American Society of Clinical Oncology
      Alexandria VA 22314
      Phone #: 571-483-1780
      800 #: 888-651-3038
      e-mail: [email protected]
      Home page: http://www.cancer.net/patient
    • Friends of Cancer Research
      2231 Crystal Drive
      Arlington VA 22202
      Phone #: 703-302-1503
      800 #: N/A
      e-mail: [email protected]
      Home page: http://www.focr.org
    • International Cancer Alliance for Research and Education
      4853 Cordell Avenue
      Bethesda MD 20814
      Phone #: 301-656-3461
      800 #: 800-422-7361
      e-mail: [email protected]
      Home page: http://www.icare.org
    • Lance Armstrong Foundation
      PO Box 161550
      Austin TX 78716-1150
      Phone #: 512-236-8820
      800 #: 866-235-7205
      e-mail: N/A
      Home page: http://www.livestrong.org
    • National Cancer Institute
      6116 Executive Blvd, MSC 8322, Room 3036A
      Bethesda MD 20892-8322
      Phone #: 301-435-3848
      800 #: 800-422-6237
      e-mail: N/A
      Home page: http://www.cancer.gov
    • National Coalition for Cancer Survivorship
      1010 Wayne Avenue
      Silver Spring MD 20910-5600
      Phone #: 301-650-9127
      800 #: 877-622-7937
      e-mail: [email protected]
      Home page: http://
    • OncoLink: The University of Pennsylvania Cancer Center Resource
      3400 Spruce Street
      Philadelphia PA 19104-4283
      Phone #: 215-349-5445
      800 #: --
      e-mail: [email protected]
      Home page: http://www.oncolink.upenn.edu
    • Rare Cancer Alliance
      1649 North Pacana Way
      Green Valley AZ 85614
      Phone #: 520-625-5495
      800 #: --
      e-mail: [email protected]
      Home page: http://www.rare-cancer.org
    • Support for People with Oral and Head and Neck Cancer, Inc.
      P.O. Box 53
      Locust Valley NY 11560-0053
      Phone #: 516-759-5333
      800 #: --
      e-mail: [email protected]
      Home page: http://www.spohnc.org
    • Wellness Community
      919 18th Street N.W.
      Washington DC 20006
      Phone #: 202-659-9709
      800 #: 888-793-9355
      e-mail: [email protected]
      Home page: http://www.thewellnesscommunity.org

    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html