Alveolar Soft Part Sarcoma / Disease

Diseases & Conditions

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Alveolar Soft Part Sarcoma

Synonyms of Alveolar Soft Part Sarcoma

Alveolar sarcoma of soft parts
ASPS
ASP sarcoma

Disorder Subdivisions

General Discussion
Alveolar soft part sarcoma (ASPS) is a rare sarcoma (malignant tumor of connective tissue) of an unclear cause. It is among the least common sarcomas, representing 0.2-1 percent of large studies of soft tissue sarcomas. Since there are approximately 8000 soft-tissue sarcomas per year that arise in the United States, this means there are on the order of 15 to 80 cases nationwide each year. It is characterized by a painless mass in the leg or buttock, with a particular affinity to travel to the lungs as multiple nodules, presumably while the sarcoma itself is still small. ASPS is very rare, because it involves a specific breaking and joining event between two chromosomes, called an unbalanced translocation. This finding is observed in essentially all ASPS examined so far. This finding cannot be passed on to children, however, as the finding occurs only in the tumor, not in the normal cells; in addition, there are no families in which multiple family members have ASPS.

Treatment is with surgery and radiation for the primary place where the sarcoma arises. For disease that travels to the lungs, sometimes surgery is possible to remove nodules, but more typically chemotherapy is the only option for treatment. This tumor tends to be resistant to standard chemotherapy, so new treatments involving new chemotherapy drugs are also a reasonable option for treatment. Interferon-alfa showed benefit in one person from Japan with ASPS. There is little other data on possible helpful chemotherapy for this tumor.
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Organizations related to Alveolar Soft Part Sarcoma

Alliance Against Alveolar Soft Part Sarcoma
141-08 Coolidge Ave
Briarwood NY 11435
Phone #: 718-523-7752
800 #: N/A
e-mail: [email protected]
Home page: http://www.alveolarspsarcoma.net/
American Cancer Society, Inc.
1599 Clifton Road NE
Atlanta GA 30329
Phone #: 404-320-3333
800 #: 800-227-2345
e-mail: N/A
Home page: http://www.cancer.org
BeatSarcoma
143 28th Street
San Francisco CA 94131
Phone #: 415-651-4473
800 #: N/A
e-mail: [email protected]
Home page: N/A
Cancer.Net
American Society of Clinical Oncology
Alexandria VA 22314
Phone #: 571-483-1780
800 #: 888-651-3038
e-mail: [email protected]
Home page: http://www.cancer.net/patient
Cure Alveolar Soft Part Sarcoma International
260 Tappan St.
Brookline MA 02445
Phone #: 617-731-1143
800 #: N/A
e-mail: [email protected]
Home page: http://cureasps.org/
Friends of Cancer Research
2231 Crystal Drive
Arlington VA 22202
Phone #: 703-302-1503
800 #: N/A
e-mail: [email protected]
Home page: http://www.focr.org
Lance Armstrong Foundation
PO Box 161550
Austin TX 78716-1150
Phone #: 512-236-8820
800 #: 866-235-7205
e-mail: N/A
Home page: http://www.livestrong.org
National Cancer Institute
6116 Executive Blvd, MSC 8322, Room 3036A
Bethesda MD 20892-8322
Phone #: 301-435-3848
800 #: 800-422-6237
e-mail: N/A
Home page: http://www.cancer.gov
National Coalition for Cancer Survivorship
1010 Wayne Avenue
Silver Spring MD 20910-5600
Phone #: 301-650-9127
800 #: 877-622-7937
e-mail: [email protected]
Home page: http://
Rare Cancer Alliance
1649 North Pacana Way
Green Valley AZ 85614
Phone #: 520-625-5495
800 #: --
e-mail: [email protected]
Home page: http://www.rare-cancer.org
Sarcoma Alliance
775 E. Blithedale #334
Mill Valley CA 94941
Phone #: 415-381-7236
800 #: --
e-mail: [email protected]
Home page: http://www.sarcomaalliance.org
Sarcoma Foundation of America
9884 Main Street
Damascus MD 20872
Phone #: 301-253-8687
800 #: --
e-mail: [email protected]
Home page: http://www.curesarcoma.org
Wellness Community
919 18th Street N.W.
Washington DC 20006
Phone #: 202-659-9709
800 #: 888-793-9355
e-mail: [email protected]
Home page: http://www.thewellnesscommunity.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html