Central Diabetes Insipidus / Disease

Diseases & Conditions

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Central Diabetes Insipidus

Synonyms of Central Diabetes Insipidus

CDI
Neurogenic Diabetes Insipidus
Neurohypophyseal Diabetes Insipidus
Vasopressin-Sensitive Diabetes Insipidus

Disorder Subdivisions

General Discussion
Central diabetes insipidus (CDI) is a rare disorder characterized by excessive thirst (polydipsia) and excessive urination (polyuria). It is not related to the more common diabetes mellitus (sugar diabetes), in which the body does not produce or properly use insulin. CDI is a distinct disorder caused by complete or partial deficiency of the arginine protein, vasopressin (AVP), which is required by the kidneys to manage water balance in the body. If affected individuals do not have access to water, dehydration may occur. Eventually, more serious symptoms can develop including changes in consciousness and confusion associated with dehydration and elevation in serum sodium concentration (hypertonic dehydration). CDI may be caused by any condition that affects the creation, transport or release of vasopressin. CDI may be inherited or acquired. In some cases, no cause can be identified (idiopathic).

Organizations related to Central Diabetes Insipidus

Diabetes Insipidus Foundation, Inc.
5203 New Prospect Court
Ellicott City MD 21043
Phone #: 410-480-0880
800 #: --
e-mail: [email protected]
Home page: http://www.diabetesinsipidus.org
March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains NY 10605
Phone #: 914-428-7100
800 #: 888-663-4637
e-mail: [email protected]
Home page: http://www.marchofdimes.com
NIH/National Institute of Diabetes, Digestive & Kidney Diseases
Endocrine Diseases Metabolic Diseases Branch
Bethesda MD 20892-3570
Phone #: 301-654-3810
800 #: --
e-mail: [email protected]
Home page: http://www.niddk.nih.gov
Pituitary Network Association (PNA)
P.O. Box 1958
Thousand Oaks CA 91358
Phone #: 805-499-9973
800 #: --
e-mail: [email protected]
Home page: http://www.pituitary.org,

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html