Diseases & Conditions


Hypoplastic Left Heart Syndrome

Synonyms of Hypoplastic Left Heart Syndrome
  • Aortic and Mitral Atresia with Hypoplasic Left Heart Syndrome
  • HLHS

Disorder Subdivisions

    General Discussion
    Hypoplastic left heart syndrome is a term used to describe a group of closely related rare heart defects that are present at birth (congenital). The normal heart has four chambers. The two upper chambers, known as atria, are separated from each other by a fibrous partition known as the atrial septum. The two lower chambers are known as ventricles and are separated from each other by the ventricular septum. Valves connect the atria (left and right) to their respective ventricles. The valves allow for blood to be pumped through the chambers. Blood travels from the right ventricle through the pulmonary artery to the lungs where it receives oxygen. The blood returns to the heart through pulmonary veins and enters the left ventricle. The left ventricle sends the now oxygen-filled blood into the main artery of the body (aorta). The aorta sends the blood throughout the body.

    Hypoplastic left heart syndrome is characterized by the underdevelopment (hypoplasia) of the chambers on the left side of the heart (i.e., left atrium and ventricle). In addition, the mitral valve, which connects these chambers to each other, is usually abnormally narrow (stenosis) or closed (atresia) and the aortic valve, which connects the heart to the major vessels that lead from the lungs (ascending aorta), may also be narrow or closed. Infants with hypoplastic left heart syndrome also have an abnormally narrow ascending aorta.

    Organizations related to Hypoplastic Left Heart Syndrome
    • American Heart Association
      National Center
      Dallas TX 75231-4596
      Phone #: 214-373-6300
      800 #: 800-242-8721
      e-mail: [email protected]
      Home page: http://www.americanheart.org
    • Birth Defect Research for Children
      930 Woodcock Rd
      Orlando FL 32803
      Phone #: 407-895-0802
      800 #: --
      e-mail: [email protected]
      Home page: http://www.birthdefects.org
    • Congenital Heart Anomalies, Support, Education, & Resources
      2112 North Wilkins Road
      Swanton OH 43558
      Phone #: 419-825-5575
      800 #: --
      e-mail: [email protected]
      Home page: http://www.csun.edu/~hcmth011/chaser/chaser-news.html
    • Congenital Heart Information Network
      1561 Clark Dr
      Yardley PA 19067
      Phone #: 215-493-3068
      800 #: --
      e-mail: [email protected]
      Home page: http://www.tchin.org
    • Fetal Hope Foundation
      9786 S Holland Street
      Littelton CO 80127
      Phone #: 303-932-0553
      800 #: 877-789-4673
      e-mail: [email protected]
      Home page: http://www.fetalhope.org
    • Kids With Heart National Association for Children's Heart Disorders, Inc.
      1578 Careful Dr
      Green Bay WI 54304-2941
      Phone #: 920-498-0058
      800 #: 800-538-5390
      e-mail: [email protected]
      Home page: http://www.kidswithheart.org
    • Little Hearts, Inc.
      P.O. Box 171
      Cromwell CT 06416
      Phone #: 860-635-0006
      800 #: 866-435-4673
      e-mail: [email protected]
      Home page: http://www.littlehearts.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: [email protected]
      Home page: http://www.netnet.net/mums/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: [email protected]
      Home page: http://www.madisonsfoundation.org
    • NIH/National Heart, Lung and Blood Institute
      31 Center Drive MSC 2480
      Bethesda MD 20892-2480
      Phone #: 301-592-8573
      800 #: --
      e-mail: [email protected]
      Home page: http://www.nhlbi.nih.gov/

    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html