Lymphedema-Distichiasis Syndrome / Disease

Diseases & Conditions

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Lymphedema-Distichiasis Syndrome

Synonyms of Lymphedema-Distichiasis Syndrome

Lymphedema with Distichiasis

Disorder Subdivisions

General Discussion
Lymphedema-distichiasis syndrome is a rare genetic multisystem disorder characterized by swelling of the legs because of fluid accumulation and the development of extra eyelashes (distichiasis). Distichiasis may range from a few extra lashes to a full set of extra eyelashes. Swelling most often affects both legs (bilateral) and usually occurs around puberty. Additional anomalies sometimes associated with this disorder include cleft palate, droopy eyelids (ptosis), abnormalities of the curved transparent outer layer of fibrous tissue covering the eyeball (cornea), cysts on the spinal cord, an abnormal sensitivity to light (photophobia), and cardiac (heart) defects. Lymphedema-distichiasis syndrome is caused by mutations of the FOXC2 gene and is inherited as an autosomal dominant trait.

Organizations related to Lymphedema-Distichiasis Syndrome

Lymphatic Research Foundation
100 Forest Avenue
East Hills NY 11548
Phone #: 516-625-9675
800 #: --
e-mail: [email protected]
Home page: http://www.lymphaticresearch.org
Lymphovenous Canada
8 Silver Ave
Ontario Intl M6R 1X8
Phone #: 416--53-3-2428
800 #: N/A
e-mail: [email protected]
Home page: http://www.lymphovenous-canada.ca
March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains NY 10605
Phone #: 914-428-7100
800 #: 888-663-4637
e-mail: [email protected]
Home page: http://www.marchofdimes.com
NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda MD 20824-0105
Phone #: 301-592-8573
800 #: --
e-mail: [email protected]
Home page: N/A
National Lipedema Association, Inc.
27 Freeman Street
Arlington MA 02474
Phone #: 781-734-0367
800 #: 800-809-2503
e-mail: [email protected]
Home page: http://www.lipedema.org
National Lymphatic and Venous Diseases Foundation, Inc.
70 Heritage Ave
Portsmouth NH 03801
Phone #: 603-334-8600
800 #: 800-301-2103
e-mail: N/A
Home page: N/A
National Lymphedema Network
Latham Square Building
Oakland CA 94612-2138
Phone #: 510-208-3200
800 #: 800-541-3259
e-mail: [email protected]
Home page: http://www.lymphnet.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html