Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Addison's Disease


Synonyms of Addison's Disease
  • Chronic Adrenocortical Insufficiency
  • Primary Adrenal Insufficiency
  • Primary Failure Adrenocortical Insufficiency

Disorder Subdivisions



    General Discussion
    Addison's disease is a rare disorder characterized by chronic, usually progressive, inadequate production of the steroid hormones cortisol and aldosterone by the outer layer of cells of the adrenal glands (adrenal cortex). Classical Addison?s disease is a consequence of the loss of both of these hormones. Cortisol affects carbohydrate metabolism connective tissue development and the amount of water in the body. Aldosterone affects the sodium and potassium ion equilibrium (electrolyte imbalance) in the body, as well as water levels and, therefore, blood pressure and blood volume. Increased excretion of water and low blood pressure (hypotension) can lead to extremely low concentrations of water in the body (dehydration). Major symptoms of Addison's disease include fatigue, gastrointestinal discomfort, and changes in skin color (pigmentation).
    .

    Organizations related to Addison's Disease
    • Addison's Disease Self-Help Group (UK)
      21 George Road
      Guildford, Surrey None GU1 4NP
      Phone #: +44- 14-830 830672
      800 #: N/A
      e-mail: feedback@adshg.org.uk
      Home page: http://www.adshg.org.uk
    • American Autoimmune Related Diseases Association, Inc.
      22100 Gratiot Avenue
      Eastpointe MI 48021
      Phone #: 586-776-3900
      800 #: 800-598-4668
      e-mail: aarda@aarda.org
      Home page: http://www.aarda.org/
    • AutoImmunity Community
      None
      None None None
      Phone #: (91-9) -552-9057
      800 #: N/A
      e-mail: bandrews@autoimmunitycommunity.org
      Home page: http://autoimmunitycommunity.org
    • Autoimmune Information Network, Inc
      PO Box 4121
      Brick NJ 08723
      Phone #: 732-664-9259
      800 #: N/A
      e-mail: autoimmunehelp@aol.com
      Home page: http://www.aininc.org
    • Congenital Adrenal Hyperplasia Trust (New Zealand)
      PO Box 29-545
      Christchurch None 8005
      Phone #: +64- 3 -3584 507
      800 #: N/A
      e-mail: CAHNZ@snap.net.nz
      Home page: N/A
    • Hormone Foundation
      8401 Connecticut Ave
      Chevy Chase MD 20815
      Phone #: --
      800 #: 800-467-6663
      e-mail: hormone@endo-society.org
      Home page: http://www.hormone.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • Medic Alert Foundation International
      2323 Colorado Avenue
      Turlock CA 95382
      Phone #: 209-669-2401
      800 #: 800-432-5378
      e-mail: Inquiries@medicalert.org
      Home page: http://www.medicalert.org
    • NIH/National Digestive Diseases Information Clearinghouse
      2 Information Way
      Bethesda MD 20892-3570
      Phone #: 301-654-3810
      800 #: 800-891-5389
      e-mail: nddic@info.niddk.nih.gov
      Home page: http://www.niddk.nih.gov
    • National Adrenal Diseases Foundation
      505 Northern Boulevard
      Great Neck NY 11021
      Phone #: 516-487-4992
      800 #: --
      e-mail: NADFmail@aol.com
      Home page: http://www.medhelp.org/nadf



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

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