Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Colitis, Collagenous


Synonyms of Colitis, Collagenous
  • Microscopic Colitis, Collagenous Type

Disorder Subdivisions



    General Discussion
    Collagenous colitis is a rare digestive disorder that primarily affects females and typically becomes apparent during middle age. The disorder is characterized by inflammatory changes of the mucous membranes (mucosa) of the colon (colitis) and abnormal accumulation (excessive deposition) of the protein collagen beneath the surface (epithelial) layer of the mucosa (thickened subepithelial collagenous bands). The colon is the major portion of the large intestine. The medical literature often refers to collagenous colitis as a form of microscopic colitis, since evidence of inflammation and other abnormalities may only be confirmed through microscopic (i.e., histologic) examination of multiple tissue samples.

    Individuals with collagenous colitis typically experience episodes of chronic, watery, nonbloody diarrhea. In some instances, episodes may often occur at night (nocturnal diarrhea). Diarrheal episodes may be persistent or may occur at intervals (intermittent) over a period of weeks, months, or years. Other symptoms and findings that may occasionally be associated with such episodes include vague abdominal pain, abdominal swelling (distension), nausea, vomiting, and/or weight loss.

    The exact cause of collagenous colitis is unknown. Possible immunological, environmental, genetic, and/or other factors are under investigation as potential causes of the disorder.
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    Organizations related to Colitis, Collagenous
    • CORE
      3 St. Andrews Place
      London None NW1 4LB
      Phone #: 020- 74-86 0341
      800 #: N/A
      e-mail: info@corecharity.org.uk
      Home page: http://www.corecharity.org.uk
    • Crohn's and Colitis Foundation of America
      386 Park Avenue South
      New York NY 10016-9804
      Phone #: 212-685-3440
      800 #: 800-932-2423
      e-mail: info@ccfa.org
      Home page: http://www.ccfa.org
    • Digestive Disease National Coalition
      507 Capitol Court
      Washington DC 20002
      Phone #: 202-544-7497
      800 #: --
      e-mail: scott@hmcw.org
      Home page: http://www.ddnc.org
    • Gastro-Intestinal Research Foundation
      70 East Lake Street
      Chicago IL 60601-5907
      Phone #: 312-332-1350
      800 #: --
      e-mail: girf@earthlink.net
      Home page: http://www.girf.org
    • International Foundation for Functional Gastrointestinal Disorders
      P.O. Box 170864
      Milwaukee WI 53217
      Phone #: 414-964-1799
      800 #: 888-964-2001
      e-mail: iffgd@iffgd.org
      Home page: http://www.iffgd.org
    • NIH/National Digestive Diseases Information Clearinghouse
      2 Information Way
      Bethesda MD 20892-3570
      Phone #: 301-654-3810
      800 #: 800-891-5389
      e-mail: nddic@info.niddk.nih.gov
      Home page: http://www.niddk.nih.gov
    • Reach Out for Youth with Ileitis and Colitis, Inc.
      84 Northgate Circle
      Melville NY 11747
      Phone #: 631-293-3102
      800 #: --
      e-mail: reachoutforyouth@reachoutforyouth.org
      Home page: http://www.reachoutforyouth.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html