Diseases & Conditions


Distal Myopathy

Synonyms of Distal Myopathy
  • Distal Muscular Dystrophy

Disorder Subdivisions

  • Distal Myopathy 3 (MPD3)
  • Distal Myopathy with Rimmed Vacuoles (DMRV)
  • Distal Myopathy with Vocal Cord and Pharyngeal Signs
  • Inclusion Body Myopathy Type 2 (IBM2)
  • Laing Distal Myopathy
  • Laing Early-Onset Distal Myopathy
  • Miyoshi Myopathy
  • Nonaka Myopathy
  • Tibial Distal Myopathy
  • Udd Distal Myopathy
  • Welander Distal Myopathy

General Discussion
Distal myopathy (or distal muscular dystrophy) is a general term for a group of rare progressive genetic disorders characterized by wasting (atrophy) and weakness of the voluntary distal muscles. The distal muscles are those farther from the center of the body and include the muscles of the lower arms and legs and the hands and feet. Conversely, the proximal muscles are the muscles closest to the center of the body such as the muscles of the shoulder, pelvis, and upper arms and legs. Although age of onset can occur anytime from infancy to adulthood, most forms develop later in life and are slowly progressive. Inheritance is autosomal dominant or recessive.

The distal myopathies belong to a larger group of disorders known as the muscular dystrophies. The muscular dystrophies are characterized by weakness and degeneration of various voluntary muscles of the body. Approximately 30 different disorders make up the muscular dystrophies. The disorders affect different muscles and have different ages of onset, severity and inheritance patterns.

Organizations related to Distal Myopathy
  • European Alliance of Neuromuscular Disorders Associations
    MDG Malta 4,
    Gzira Intl GAR 04
    Phone #: 003-56 -21 346688
    800 #: --
    e-mail: eamda@hotmail.com
    Home page: http://www.eamda.net
  • Jain Foundation Inc.
    2889 152nd Ave NE
    Redmond WA 98052
    Phone #: 425-882-1492
    800 #: N/A
    e-mail: plavimittal@jain-foundation.org
    Home page: http://www.jain-foundation.org
  • March of Dimes Birth Defects Foundation
    1275 Mamaroneck Avenue
    White Plains NY 10605
    Phone #: 914-428-7100
    800 #: 888-663-4637
    e-mail: Askus@marchofdimes.com
    Home page: http://www.marchofdimes.com
  • Muscular Dystrophy Association
    3300 E. Sunrise Dr
    Tucson AZ 85718
    Phone #: 520-529-2000
    800 #: 800-344-4863
    e-mail: mda@mdausa.org
    Home page: http://www.mdausa.org
  • Muscular Dystrophy Association (Australia)
    GPO Box 9932
    Melbourne Intl 3001
    Phone #: 61 -3 9-320 9555
    800 #: 1 8-00 -656 632
    e-mail: info@mda.org.au
    Home page: http://www.mda.org.au
  • Muscular Dystrophy Association of New Zealand, Inc.
    PO Box 23-047
    Auckland None None
    Phone #: 09 -278-7216
    800 #: 080-080-0337
    e-mail: nzmda@nzmda.ak.planet.gen.nz
    Home page: N/A
  • Muscular Dystrophy Campaign
    7-11 Prescott Place
    London None SW4 6BS
    Phone #: N/A
    800 #: --
    e-mail: info@muscular-dystrophy.org
    Home page: http://www.muscular-dystrophy.org
  • Muscular Dystrophy Canada
    900-2345 Yonge Street
    Ontario Intl M4P 2E5
    Phone #: 416--48-8-0030
    800 #: (86-6)--MUSCLE-8
    e-mail: info@muscle.ca
    Home page: http://www.muscle.ca
  • Muscular Dystrophy Ireland
    71/72 North Brunswich Street
    Dublin 7 Intl None
    Phone #: 353- 1 -8721501
    800 #: --
    e-mail: info@mdi.ie
    Home page: http://www.mdi.ie/
  • National Institute of Neurological Disorders and Stroke (NINDS)
    31 Center Drive
    Bethesda MD 20892-2540
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: braininfo@ninds.nih.gov
    Home page: http://www.ninds.nih.gov/

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html