Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Granulomatous Disease, Chronic


Synonyms of Granulomatous Disease, Chronic
  • CGD
  • Chronic Dysphagocytosis
  • Chronic Granulomatous Disease
  • Congenital Dysphagocytosis
  • Fatal Granulomatous Disease of Childhood
  • Granulomatosis, Chronic, Familial
  • Granulomatosis, Septic, Progressive
  • Impotent Neutrophil Syndrome

Disorder Subdivisions



    General Discussion
    Chronic granulomatous disease (CGD) is a rare inherited primary immune deficiency disorder that affects certain white blood corpuscles (neutrophils, monocytes, macrophages, eosinophils). The disorder is characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, and bones may occur along with swollen areas of inflamed tissues known as granulomas that can be widely distributed. Symptoms usually begin in infancy or childhood. Individuals with mild forms of the disorder may not develop symptoms until the teens or adulthood. Chronic granulomatous disease is a genetic disorder and is caused by inherited defects in an important enzyme in white blood cells that manufactures oxidants for microbial killing.

    Organizations related to Granulomatous Disease, Chronic
    • Chronic Granulomatous Disease Association, Inc.
      2616 Monterey Road
      San Marino CA 91108-1646
      Phone #: 626-441-4118
      800 #: --
      e-mail: cgda@socal.rr.com
      Home page: http://www.cgdassociation.org
    • Chronic Granulomatous Disease Registry
      c/o Immune Deficiency Foundation
      Towson MD 21204
      Phone #: 410-321-6647
      800 #: 800-296-4433
      e-mail: idf@primaryimmune.org
      Home page: http://www.primaryimmune.org
    • Chronic Granulomatous Disorder Research Trust (CGD)
      The CGD Office
      Dorset Intl BH21 5NL
      Phone #: 004-417-25517977
      800 #: N/A
      e-mail: cgdresearchtrust@dial.pipex.com
      Home page: http://www.cgd.org.uk
    • European Society for Immunodeficiencies (ESID)
      c/o Dr. Esther de Vries
      Hertogenbosch None 5200 ME's
      Phone #: +31- 73--6992965
      800 #: N/A
      e-mail: info@esid.org
      Home page: http://www.esid.org
    • Immune Deficiency Foundation
      40 West Chesapeake Avenue
      Towson MD 21204
      Phone #: 410-321-6647
      800 #: 800-296-4433
      e-mail: idf@primaryimmune.org
      Home page: http://www.primaryimmune.org
    • International Patient Organization for Primary Immunodeficiencies
      Firside
      Cornwall None PL11 3LE
      Phone #: 44 -150-3 250 668
      800 #: --
      e-mail: info@ipopi.org
      Home page: http://www.ipopi.org/
    • Jeffrey Modell Foundation
      747 Third Ave
      New York NY 10017
      Phone #: 212-819-0200
      800 #: 866-469-6474
      e-mail: info@jmfworld.org
      Home page: http://www.info4pi.org
    • NIH/National Institute of Allergy and Infectious Diseases
      6610 Rockledge Drive
      Bethesda MD 20892-6612
      Phone #: 301-496-5717
      800 #: --
      e-mail: N/A
      Home page: http://www.niaid.nih.gov/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html