Diseases & Conditions


Henoch-Schonlein Purpura

Synonyms of Henoch-Schonlein Purpura
  • Allergic Purpura
  • Allergic Vasculitis
  • Anaphylactoid Purpura
  • Hemorrhagic Capillary Toxicosis
  • Henoch-Schonlein Purpura
  • HSP
  • Leukocytoclastic Vasculitis
  • Nonthrombocytopenic Idiopathic Purpura
  • Peliosis Rheumatica
  • Rheumatic Purpura
  • Schonlein-Henoch Purpura

Disorder Subdivisions

  • Henoch's Purpura
  • Schonlein's Purpura

General Discussion
Henoch-Schonlein purpura is a rare inflammatory disease of the small blood vessels (capillaries) and is usually a self-limited disease. It is the most common form of childhood vascular inflammation (vasculitis) and results in inflammatory changes in the small blood vessels. The symptoms of Henoch-Schonlein purpura usually begin suddenly and may include headache, fever, loss of appetite, cramping abdominal pain, and joint pain. Red or purple spots typically appear on the skin (petechial purpura). Inflammatory changes associated with Henoch-Schonlein purpura can also develop in the joints, kidneys, digestive system, and, in rare cases, the brain and spinal cord (central nervous system).

In one form of the disorder, termed Schonlein's purpura, the skin and joints are affected but the gastrointestinal tract is not. In another form, known as Henoch's purpura, affected individuals have purplish spots on the skin and acute abdominal problems. People with Henoch's purpura are not affected by joint disease.

The exact cause of Henoh-Schonlein purpura is not fully understood, although research suggests that it may be an autoimmune disease or, in some rare cases, an extreme allergic reaction to certain offending substances (e.g., foods or drugs).

Organizations related to Henoch-Schonlein Purpura
  • American Autoimmune Related Diseases Association, Inc.
    22100 Gratiot Avenue
    Eastpointe MI 48021
    Phone #: 586-776-3900
    800 #: 800-598-4668
    e-mail: aarda@aarda.org
    Home page: http://www.aarda.org/
  • American Kidney Fund, Inc.
    6110 Executive Boulevard
    Rockville MD 20852
    Phone #: 301-881-3052
    800 #: 800-638-8299
    e-mail: helpline@kideyfund.org
    Home page: http://www.kidneyfund.org
  • AutoImmunity Community
    None None None
    Phone #: (91-9) -552-9057
    800 #: N/A
    e-mail: bandrews@autoimmunitycommunity.org
    Home page: http://autoimmunitycommunity.org
  • Kidney & Urology Foundation of America, Inc.
    152 Madison Ave.
    New York NY 10016
    Phone #: 212-629-9770
    800 #: 800-633-6628
    e-mail: info@kidneyurology.org
    Home page: http://www.kidneyurology.org
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • NIH/National Heart, Lung and Blood Institute Information Center
    P.O. Box 30105
    Bethesda MD 20824-0105
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: N/A
  • NIH/National Institute of Allergy and Infectious Diseases
    6610 Rockledge Drive
    Bethesda MD 20892-6612
    Phone #: 301-496-5717
    800 #: --
    e-mail: N/A
    Home page: http://www.niaid.nih.gov/
  • National Kidney Foundation
    30 East 33rd Street
    New York NY 10016
    Phone #: 212-889-2210
    800 #: 800-622-9010
    e-mail: info@kidney.org
    Home page: http://www.kidney.org
  • Platelet Disorder Support Association
    133 Rollins Avenue
    Rockville MD 20852
    Phone #: 301-770-6636
    800 #: 877-528-3538
    e-mail: pdsa@pdsa.org
    Home page: http://www.pdsa.org
  • Vasculitis Foundation
    P.O. Box 28660
    Kansas City MO 64188
    Phone #: 816-436-8211
    800 #: 800-277-9474
    e-mail: vf@vasculitisfoundation.org
    Home page: http://www.vasculitisfoundation.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html