Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Hereditary Exostoses, Multiple


Synonyms of Hereditary Exostoses, Multiple
  • Diaphyseal Aclasis
  • EXT
  • External Chondromatosis Syndrome
  • Multiple Cartilaginous Exostoses
  • Multiple Exostoses
  • Multiple Exostoses Syndrome
  • Multiple Osteochondromatosis

Disorder Subdivisions



    General Discussion
    Hereditary multiple exostoses (HME) is a rare genetic disorder characterized by multiple bony growths or tumors (exostoses), often on the growing end (metaphysis) of the long bones of the legs, arms, and digits. These bony growths are covered by cartilage and usually continue to grow until shortly after puberty. Exostoses may lead to bone deformities, skeletal abnormalities, short stature, nerve compression and reduced range of motion. Hereditary multiple exostoses is inherited as an autosomal dominant genetic condition and is associated with abnormalities (mutations) in the EXT1 and EXT 2 genes.

    Organizations related to Hereditary Exostoses, Multiple
    • MHE Coalition
      8838 Holly Lane
      Olmsted Falls OH 44138-2701
      Phone #: 440-235-6325
      800 #: --
      e-mail: CheleZ1@aol.com
      Home page: http://www.mhecoalition.com
    • MHE Research Foundation
      79-77 Street
      Brooklyn NY 11209
      Phone #: 718-569-0479
      800 #: 877-486-1758
      e-mail: sarahziegler@mheresearchfoundation.org
      Home page: http://mheresearchfoundation.org
    • MHE and Me- A Support Group for Kids with Multiple Hereditary Exostoses
      14 Stony Brook Dr
      Pine Island NY 10969
      Phone #: 845-258-6058
      800 #: --
      e-mail: mheandme@yahoo.com
      Home page: http://www.geocities.com/mheandme
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
      1 AMS Circle
      Bethesda MD 20892-3675
      Phone #: 301-495-4484
      800 #: 877-226-4267
      e-mail: NIAMSinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html