Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Holt Oram Syndrome


Synonyms of Holt Oram Syndrome
  • atriodigital dysplasia
  • heart-hand syndrome
  • HOS1

Disorder Subdivisions



    General Discussion
    Holt-Oram syndrome is a disorder that is characterized by abnormalities in the bones of the upper limb and a family or personal history of a congenital heart malformation or an abnormality in the electrical impulses that coordinate the muscle contraction of the heart (cardiac conduction defect). In some affected individuals, an abnormal wrist (carpal) bone is the only evidence of the disease. Seventy-five percent of those affected have a congenital heart malformation. Holt-Oram syndrome is an autosomal dominant genetic condition that is associated with an abnormality in the TBX5 gene.

    Organizations related to Holt Oram Syndrome
    • American Heart Association
      National Center
      Dallas TX 75231-4596
      Phone #: 214-373-6300
      800 #: 800-242-8721
      e-mail: inquire@heart.org
      Home page: http://www.americanheart.org
    • Congenital Heart Anomalies, Support, Education, & Resources
      2112 North Wilkins Road
      Swanton OH 43558
      Phone #: 419-825-5575
      800 #: --
      e-mail: chaser@compuserve.com
      Home page: http://www.csun.edu/~hcmth011/chaser/chaser-news.html
    • Congenital Heart Information Network
      1561 Clark Dr
      Yardley PA 19067
      Phone #: 215-493-3068
      800 #: --
      e-mail: mb@tchin.org
      Home page: http://www.tchin.org
    • Kids With Heart National Association for Children's Heart Disorders, Inc.
      1578 Careful Dr
      Green Bay WI 54304-2941
      Phone #: 920-498-0058
      800 #: 800-538-5390
      e-mail: kidswithheart@greenbaynet.com
      Home page: http://www.kidswithheart.org
    • Little Hearts, Inc.
      P.O. Box 171
      Cromwell CT 06416
      Phone #: 860-635-0006
      800 #: 866-435-4673
      e-mail: info@littlehearts.org
      Home page: http://www.littlehearts.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
      1 AMS Circle
      Bethesda MD 20892-3675
      Phone #: 301-495-4484
      800 #: 877-226-4267
      e-mail: NIAMSinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info
    • NIH/National Heart, Lung and Blood Institute Information Center
      P.O. Box 30105
      Bethesda MD 20824-0105
      Phone #: 301-592-8573
      800 #: --
      e-mail: nhlbiinfo@rover.nhlbi.nih.gov
      Home page: N/A
    • Reach: The Association for Children with Hand or Arm Deficiency
      P.O. Box 54
      Cornwall, Intl TR13 8WD
      Phone #: 084-5 1-306225
      800 #: --
      e-mail: reach@reach.org.uk
      Home page: http://www.reach.org.uk



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html