Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Malignant Hyperthermia


Synonyms of Malignant Hyperthermia
  • Hyperpyrexia

Disorder Subdivisions



    General Discussion
    Malignant Hyperthermia (MH) is a pharmacogenetic channelopathy affecting skeletal muscle. When MH-susceptible individual are given potent inhalational agents (halothane, sevoflurane, desflurane, etc.) and/or succinylcholine, they can develop a hypermetabolic state that can rapidly progress to a high temperature, muscle rigidity, cardiac arrest, and ultimately may lead to death.

    Organizations related to Malignant Hyperthermia
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • Malignant Hyperthermia Association of the United States (MHAUS)
      11 East State Street
      Sherburne NY 13460-1069
      Phone #: 607-674-7901
      800 #: --
      e-mail: info@mhaus.org
      Home page: http://www.mhaus.org
    • Malignant Hyperthermia Hotline
      MHAUS Hotline (available 24 hours a day)
      None None 95382
      Phone #: --
      800 #: 800-644-9737
      e-mail: N/A
      Home page: http://www.mhaus.org
    • Malignant Hyperthermia Investigation Unit
      Toronto General Hospital
      Ontario Intl M5G 2C4
      Phone #: (41-6)3-40-3128
      800 #: --
      e-mail: info@mhacanada.org
      Home page: http://www.mhacanada.org
    • NIH/National Institute of General Medical Sciences
      45 Center Dr MSC 6200
      Bethesda MD 20892-6200
      Phone #: 301-496-7301
      800 #: --
      e-mail: N/A
      Home page: N/A
    • North American Malignant Hyperthermia Registry of MHAUS
      Children's Hospital of Pittsburgh
      Pittsburgh PA 15213-2583
      Phone #: 412-692-6390
      800 #: 888-274-7899
      e-mail: bwb+@pitt.edu
      Home page: http://www.mhreg.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html