Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Mediterranean Fever, Familial


Synonyms of Mediterranean Fever, Familial
  • Armenian Syndrome
  • Benign Paroxysmal Peritonitis
  • Familial Paroxysmal Polyserositis
  • FMF
  • MEF
  • Periodic Amyloid Syndrome
  • Periodic Peritonitis Syndrome
  • Polyserositis, Recurrent
  • Reimann Periodic Disease
  • Reimann's Syndrome
  • Siegel-Cattan-Mamou Syndrome

Disorder Subdivisions



    General Discussion
    Familial Mediterranean fever (FMF) is a rare, inherited, inflammatory disease characterized by recurrent attacks of fever and acute inflammation of the membranes that line the abdominal cavity (peritonitis) and/or the lungs (pleuritis); pain and swelling of the joints (arthritis); and/or the heart (pericarditis) and, in some cases, skin rashes. In addition, some affected individuals may experience a serious complication known as amyloidosis, which is characterized by abnormal accumulation of a fatty-like substance (amyloid) in various parts of the body. If amyloid accumulates in the kidneys (renal amyloidosis), kidney function may be impaired and life-threatening complications may occur.

    In most instances, but not exclusively, FMF affects persons of Mediterranean origin such as Sephardic Jews, Arabs, Armenians, and Turks. FMF is inherited as an autosomal recessive trait. The causative gene on the short arm of chromosome 16 has been cloned.

    Organizations related to Mediterranean Fever, Familial
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • Madisons Foundation
      PO Box 241956
      Los Angeles CA 90024
      Phone #: 310-264-0826
      800 #: N/A
      e-mail: getinfo@madisonsfoundation.org
      Home page: http://www.madisonsfoundation.org
    • March of Dimes Birth Defects Foundation
      1275 Mamaroneck Avenue
      White Plains NY 10605
      Phone #: 914-428-7100
      800 #: 888-663-4637
      e-mail: Askus@marchofdimes.com
      Home page: http://www.marchofdimes.com
    • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
      1 AMS Circle
      Bethesda MD 20892-3675
      Phone #: 301-495-4484
      800 #: 877-226-4267
      e-mail: NIAMSinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info
    • NIH/National Digestive Diseases Information Clearinghouse
      2 Information Way
      Bethesda MD 20892-3570
      Phone #: 301-654-3810
      800 #: 800-891-5389
      e-mail: nddic@info.niddk.nih.gov
      Home page: http://www.niddk.nih.gov



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html