Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Motor Neuron Disease


Synonyms of Motor Neuron Disease
  • Motoneuron Disease
  • Motoneurone Disease
  • Motor Neurone Disease
  • Motor Neuron Syndrome

Disorder Subdivisions

  • ALS Included
  • Amyotrophic Lateral Sclerosis
  • Benign Focal Amyotrophy
  • Duchenne's Paralysis
  • Infantile Spinal Muscular Atrophy (all types)
  • Juvenile Spinal Muscular Atrophy
  • Kugelberg-Welander Syndrome
  • Lou Gehrig's Disease, Included
  • Progressive Bulbar Palsy
  • Spinal Muscular Atrophy, All Types
  • Werdnig-Hoffmann Disease


General Discussion
Motor neuron disease comprises a group of severe disorders of the nervous system characterized by progressive degeneration of motor neurons (neurons are the basic nerve cells that combine to form nerves). Motor neurons control the behavior of muscles. Motor neuron diseases may affect the upper motor neurons, nerves that lead from the brain to the medulla (a part of the brain stem) or to the spinal cord, or the lower motor neurons, nerves that lead from the spinal cord to the muscles of the body, or both. Spasms and exaggerated reflexes indicate damage to the upper motor neurons. A progressive wasting (atrophy) and weakness of muscles that have lost their nerve supply indicate damage to the lower motor neurons.

Organizations related to Motor Neuron Disease
  • Amyotrophic Lateral Sclerosis Association
    27001 Agoura Road
    Calabasas Hills CA 91301-5104
    Phone #: 818-880-9007
    800 #: 800-782-4747
    e-mail: als@alsa-national.org
    Home page: http://www.alsa.org
  • Association for Frontotemporal Dementias (AFTD)
    1616 Walnut Street, Suite 1100
    Philadelphia PA 19103
    Phone #: 267-514-7221
    800 #: 866-507-7222
    e-mail: info@ftd-picks.org
    Home page: http://www.ftd-picks.org
  • Families of Spinal Muscular Atrophy
    P.O. Box 196
    Libertyville IL 60048
    Phone #: 847-367-7620
    800 #: 800-886-1762
    e-mail: sma@fsma.org
    Home page: http://www.curesma.com
  • International Alliance of ALS/MND Associations
    None
    Northampton None NN1 2PR
    Phone #: N/A
    800 #: --
    e-mail: alliance@alsmndalliance.org
    Home page: http://www.alsmndalliance.org/
  • Motor Neurone Disease Association
    P.O. Box 246
    Northampton Intl NN1 2PR
    Phone #: 44 -160-4 250505
    800 #: --
    e-mail: enquiries@mndassociation.org
    Home page: http://www.mndassociation.org
  • Muscular Dystrophy Association
    3300 E. Sunrise Dr
    Tucson AZ 85718
    Phone #: 520-529-2000
    800 #: 800-344-4863
    e-mail: mda@mdausa.org
    Home page: http://www.mdausa.org
  • National Institute of Neurological Disorders and Stroke (NINDS)
    31 Center Drive
    Bethesda MD 20892-2540
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: braininfo@ninds.nih.gov
    Home page: http://www.ninds.nih.gov/
  • Scottish Motor Neurone Disease Association
    76 Firhill Rd
    Glasgow Intl G20 7BA
    Phone #: 014-194-51077
    800 #: N/A
    e-mail: info@scotmnd.co.uk
    Home page: http://www.scotmnd.org.uk



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html