Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Multiple System Atrophy


Synonyms of Multiple System Atrophy
  • MSA

Disorder Subdivisions

  • Progressive Autonomic Failure with Multiple System Atrophy
  • Shy-Drager Syndrome (SDS)
  • Sporadic Olivopontocerebellar Atrophy
  • Sporadic OPCA
  • Striatonigral Degeneration (SND)


General Discussion
Multiple system atrophy (MSA) is a rare progressive neurological disorder characterized by a varying combination of symptoms. Affected individuals may experience symptoms similar to those found in Parkinson?s disease (parkinsonism); cerebellar signs such as progressive impairment of the ability to coordinate voluntary movements (cerebellar ataxia); and impaired functioning of the portion of the nervous system (autonomic nervous system) that regulates certain involuntary body functions (autonomic failure) such as heart rate, blood pressure, sweating, and bowel and bladder control. The exact cause of multiple system atrophy is unknown.

The term multiple system atrophy has generated significant controversy and confusion in the medical literature. The term now encompasses three conditions once thought to be separate disorders, specifically Shy-Drager syndrome, striatonigral degeneration, and sporadic olivopontocerebellar atrophy. Additionally, there is a hereditary form of olivopontocerebellar atrophy that is not part of the multiple system atrophy spectrum.
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Organizations related to Multiple System Atrophy
  • Autonomic Dysfunction Center
    Vanderbilt University Medical Center
    Nashville TN 37232-2195
    Phone #: 615-343-6499
    800 #: --
    e-mail: david.robertson@vanderbilt.edu
    Home page: http://www.mc.vanderbilt.edu/gcrc/adc
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • National Dysautonomia Research Foundation
    PO Box 301
    Red Wing MN 55066-0102
    Phone #: 651-267-0525
    800 #: --
    e-mail: ndrf@ndrf.org
    Home page: http://www.ndrf.org
  • National Institute of Neurological Disorders and Stroke (NINDS)
    31 Center Drive
    Bethesda MD 20892-2540
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: braininfo@ninds.nih.gov
    Home page: http://www.ninds.nih.gov/
  • National Parkinson Foundation, Inc.
    1501 NW 9th Ave/Bob Hope Road
    Miami FL 33136-1494
    Phone #: 305-243-6666
    800 #: 800-327-4545
    e-mail: contact@parkinson.org
    Home page: http://www.parkinson.org
  • Parkinson's Disease Foundation, Inc.
    1359 Broadway
    New York NY 10018
    Phone #: 212-923-4700
    800 #: 800-457-6676
    e-mail: info@pdf.org
    Home page: http://www.pdf.org
  • Shy-Drager Syndrome/Multiple System Atrophy Support Group
    P.O. Box 279
    Coupland TX 78615
    Phone #: N/A
    800 #: 866-737-4999
    e-mail: don.summers@shy-drager.org
    Home page: http://www.shy-drager.org/
  • WE MOVE (Worldwide Education and Awareness for Movement Disorders)
    204 West 84th Street
    New York NY 10024
    Phone #: 212-875-8312
    800 #: N/A
    e-mail: wemove@wemove.org
    Home page: http://www.wemove.org



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html