Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Oral-Facial-Digital Syndrome


Synonyms of Oral-Facial-Digital Syndrome
  • OFD Syndrome
  • Orofaciodigital Syndrome

Disorder Subdivisions

  • OFDS Type III (Sugarman Syndrome)
  • OFDS Type II (Mohr Syndrome)
  • OFDS Type I (Papillon-Leage-Psaume Syndrome)
  • OFDS Type IV (Baraitser-Burn Syndrome
  • OFDS Type IX (OFD Syndrome with Retinal Abnormalities)
  • OFDS Type VIII (Edwards Syndrome)
  • OFDS Type VII (Whelan Syndrome)
  • OFDS Type VI (Varadi Syndrome)
  • OFDS Type V (Thurston Syndrome)
  • OFDS Type X (OFD with Fibular Aplasia)


General Discussion
Oral-facial-digital syndrome (OFDS) is an umbrella term for at least 10 apparently distinctive genetic disorders that are characterized by defects and flaws in the development of the structure of the oral cavity including the mouth, tongue, teeth, and jaw; the development of the facial structures including the head, eyes, and nose; and the fingers and toes (digits); along with differing degrees of mental retardation. The presentation of signs and symptoms is extremely varied, making diagnosis difficult. OFDS type I is the most common of all of these disorders, and it is quite rare. Each of the other types is extremely rare.

Organizations related to Oral-Facial-Digital Syndrome
  • AmeriFace
    PO Box 751112
    Las Vegas NV 89136
    Phone #: 702-769-9264
    800 #: 888-486-1209
    e-mail: info@ameriface.org
    Home page: http://www.ameriface.org
  • Children's Craniofacial Association
    13140 Coit Road
    Dallas TX 75240
    Phone #: 214-570-9099
    800 #: 800-535-3643
    e-mail: csmith@ccakids.com
    Home page: http://www.ccakids.com
  • FACES: The National Craniofacial Association
    P.O. Box 11082
    Chattanooga TN 37401
    Phone #: 423-266-1632
    800 #: 800-332-2373
    e-mail: faces@faces-cranio.org
    Home page: http://www.faces-cranio.org
  • Forward Face, Inc.
    317 East 34th Street
    New York NY 10016
    Phone #: 212-684-5860
    800 #: 800-393-3223
    e-mail: info@forwardface.org
    Home page: http://www.forwardface.org
  • Let's Face It (USA)
    P.O. Box 29972
    Bellingham WA 98228-1972
    Phone #: 360-676-7325
    800 #: --
    e-mail: faceit@umich.edu
    Home page: http://www.dent.umich.edu/faceit
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • NIH/National Oral Health Information Clearinghouse
    1 NOHIC Way
    Bethesda MD 20892-3500
    Phone #: 301-402-7364
    800 #: --
    e-mail: nohic@nidcr.nih.gov
    Home page: http://www.nohic.nidcr.nih.gov
  • National Foundation for Ectodermal Dysplasias
    410 East Main Street
    Mascoutah IL 62258-0114
    Phone #: 618-566-2020
    800 #: --
    e-mail: info@nfed.org
    Home page: http://www.nfed.org
  • National Foundation for Facial Reconstruction
    317 East 34th St.
    New York NY 10016
    Phone #: 212-263-6656
    800 #: 800-422-3223
    e-mail: whitney@nffr.org
    Home page: http://www.nffr.org
  • National Foundation of Dentistry For the Handicapped
    1800 15th Street
    Denver CO 80202
    Phone #: 303-534-5360
    800 #: --
    e-mail: fleviton@nfdh.org
    Home page: http://www.nfdh.org
  • Prescription Parents
    Prescription Parent, Inc.
    Needham MA 02492
    Phone #: 617-499-1936
    800 #: --
    e-mail: info@prescriptionparents.org
    Home page: http://www.prescriptionparents.com
  • The Arc (a national organization on mental retardation)
    1010 Wayne Ave
    Silver Spring MD 20910
    Phone #: 301-565-3842
    800 #: 800-433-5255
    e-mail: info@thearc.org
    Home page: http://www.thearc.org/



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html