Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Osteonecrosis


Synonyms of Osteonecrosis
  • Aseptic Necrosis
  • Avascular Necrosis of Bone
  • Ischemic Necrosis of Bone

Disorder Subdivisions



    General Discussion
    Osteonecrosis, also known as avascular necrosis, is a disease resulting from the temporary or permanent loss of the blood supply to the bones. Without blood, the bone tissue dies and causes the bone to collapse. If the process involves the bones near a joint, it often leads to collapse of the joint surface. This disease also is known, aseptic necrosis, and ischemic bone necrosis.

    Although it can happen in any bone, osteonecrosis most commonly affects the ends (epiphysis) of long bones such as the femur, the bone extending from the knee joint to the hip joint. Other common sites include the upper arm bone, knees, shoulders, and ankles. The disease may affect just one bone, more than one bone at the same time, or more than one bone at different times. Orthopaedic doctors most often diagnose the disease.

    The amount of disability that results from osteonecrosis depends on what part of the bone is affected, how large an area is involved, and how effectively the bone rebuilds itself. The process of bone rebuilding takes place after an injury as well as during normal growth. Normally, bone continuously breaks down and rebuilds--old bone is reabsorbed and replaced with new bone. The process keeps the skeleton strong and helps it to maintain a balance of minerals. In the course of osteonecrosis, however, the healing process is usually ineffective and the bone tissues break down faster than the body can repair them. If left untreated, the disease progresses, the bone collapses, and the joint surface breaks down, leading to pain and arthritis.

    Organizations related to Osteonecrosis
    • American Academy of Orthopaedic Surgeons
      6300 North River Road
      Rosemont IL 60018-4262
      Phone #: 847-823-7186
      800 #: --
      e-mail: webhelp@aaos.org
      Home page: http://www.aaos.org/
    • Arthritis Foundation
      1330 West Peachtree Street
      Atlanta GA 30309
      Phone #: 404-872-7100
      800 #: 800-568-4045
      e-mail: help@arthritis.org
      Home page: http://www.arthritis.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
      1 AMS Circle
      Bethesda MD 20892-3675
      Phone #: 301-495-4484
      800 #: 877-226-4267
      e-mail: NIAMSinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info
    • NIH/Osteoporosis and Related Bone Diseases - National Resource Center
      2 AMS Circle
      Bethesda MD 20892-3676
      Phone #: 202-223-0344
      800 #: 800-624-2663
      e-mail: niamsboneinfo@mail.nih.gov
      Home page: http://www.niams.nih.gov/Health_Info/Bone/
    • National Osteonecrosis Foundation
      c/o NONF Suite 201
      Baltimore MD 21239
      Phone #: 410-532-5985
      800 #: --
      e-mail: N/A
      Home page: http://www.nonf.org



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html