Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Paraneoplastic Neurologic Syndromes


Synonyms of Paraneoplastic Neurologic Syndromes
  • No synonyms found

Disorder Subdivisions

  • No synonyms found


General Discussion
Paraneoplastic neurologic syndromes (PNS) are a group of conditions that affect the nervous system (brain, spinal cord, nerves and/or muscles) in patients with cancer. The term paraneoplastic means that the neurological syndrome is not caused by the tumor itself, but by the immunological reactions that the tumor produces. It is believed that the body?s normal immunological system interprets the tumor as an invasion. When this occurs, the immunological system mounts an immune response, utilizing antibodies and lymphocytes to fight the tumor. The end result is that the patient?s own immune system can cause collateral damage to the nervous system, which can sometimes be severe. In many patients, the immune response can cause nervous system damage that far exceeds the damage done to the tumor. The effects of PNS can remit entirely, although there can also be permanent effects.

Organizations related to Paraneoplastic Neurologic Syndromes
  • National Cancer Institute
    6116 Executive Blvd, MSC 8322, Room 3036A
    Bethesda MD 20892-8322
    Phone #: 301-435-3848
    800 #: 800-422-6237
    e-mail: N/A
    Home page: http://www.cancer.gov
  • National Institute of Neurological Disorders and Stroke (NINDS)
    31 Center Drive
    Bethesda MD 20892-2540
    Phone #: 301-496-5751
    800 #: 800-352-9424
    e-mail: braininfo@ninds.nih.gov
    Home page: http://www.ninds.nih.gov/
  • Wellness Community
    919 18th Street N.W.
    Washington DC 20006
    Phone #: 202-659-9709
    800 #: 888-793-9355
    e-mail: help@thewellnesscommunity.org
    Home page: http://www.thewellnesscommunity.org



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html