Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Russell Silver Syndrome (RSS)


Synonyms of Russell Silver Syndrome (RSS)
  • RSS
  • Russell-Silver Dwarfism
  • Russell Syndrome
  • Silver-Russell Dwarfism
  • Silver-Russell Syndrome
  • Silver Syndrome
  • SRS

Disorder Subdivisions

  • Russell-Silver Syndrome, X-linked (Partington Syndrome)


General Discussion
Russell-Silver syndrome (RSS) is a rare genetic disorder characterized by a wide variety of symptoms. RSS is genetically heterogeneous, meaning that different genetic abnormalities are believed to cause the disorder. RSS is characterized by a wide spectrum of symptoms and physical findings that vary in range and severity from case to case. The characteristic findings are growth delays before birth (prenatal or intrauterine growth retardation) and after birth (postnatal growth deficiency). Growth deficiency often results in short stature in adulthood. Additional common symptoms include unusual, distinctive facial features, a pinky that is fixed or 'locked' in a bent position (clinodactyly), and undergrowth of one side or structure of the body (hemihypotrophy), resulting in unequal (asymmetric) growth. Many children with RSS have normal intelligence, but rowing evidence suggests that there is an increased risk of learning disabilities. In most cases, the exact underlying genetic cause of RSS is not known.

Organizations related to Russell Silver Syndrome (RSS)
  • Human Growth Foundation
    997 Glen Cove Avenue
    Glen Head NY 11545
    Phone #: 516-671-4041
    800 #: 800-451-6434
    e-mail: hgf1@hgfound.org
    Home page: http://www.hgfound.org/
  • Little People of America, Inc.
    250 El Camino Real
    Tustin CA 92780
    Phone #: 714-368-3689
    800 #: 888-572-2001
    e-mail: info@lpaonline.org
    Home page: http://www.lpaonline.org
  • MAGIC Foundation for Children's Growth
    6645 W. North Avenue
    Oak Park IL 60302
    Phone #: 708-383-0808
    800 #: 800-362-4423
    e-mail: mary@magicfoundation.org
    Home page: http://www.magicfoundation.org
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
    1 AMS Circle
    Bethesda MD 20892-3675
    Phone #: 301-495-4484
    800 #: 877-226-4267
    e-mail: NIAMSinfo@mail.nih.gov
    Home page: http://www.niams.nih.gov/Health_Info
  • Restricted Growth Association
    P.O. Box 4744
    Dorset Intl DT2 9FA
    Phone #: 013-08 -898445
    800 #: --
    e-mail: N/A
    Home page: http://www.restrictedgrowth.co.uk
  • The Arc (a national organization on mental retardation)
    1010 Wayne Ave
    Silver Spring MD 20910
    Phone #: 301-565-3842
    800 #: 800-433-5255
    e-mail: info@thearc.org
    Home page: http://www.thearc.org/



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html