Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Sickle Cell Disease


Synonyms of Sickle Cell Disease
  • Sickle Cell Anemia
  • Sickle Cell Trait

Disorder Subdivisions

  • Sickle Cell-Hemoglobin C Disease
  • Sickle Cell-Hemoglobin D Disease
  • Sickle Cell-Thalassemia Disease


General Discussion
Sickle cell disease is a rare inherited blood disorder. It is characterized by the presence of sickle or crescent shaped red blood cells (erythrocytes) in the bloodstream. These abnormally-shaped cells become rigid and lodge themselves in the very tiny blood vessels (capillaries) of the peripheral blood system (blood vessels outside of the heart). The capillaries become clogged, preventing the normal flow of oxygen to tissues. Common symptoms associated with sickle cell disease include chest pain, frequent infections, yellowing of the skin (jaundice), and low levels of circulating red blood cells (anemia). Sickle cell disease has several recognized forms including sickle cell anemia, sickle cell hemoglobin C disease and sickle cell thalassemia disease. Sickle cell disease is inherited as an autosomal recessive trait.

Organizations related to Sickle Cell Disease
  • Anemia Institute for Research and Education
    151 Bloor Street West
    Toronto, Ontario None M5S 1S4
    Phone #: 416--96-9-7431
    800 #: 877--99-2-6364
    e-mail: info@anemiainstitute.org
    Home page: http://www.anemiainstitute.org
  • Cochrane Cystic Fibrosis and Genetic Disorders Review Group
    Institute of Child Health
    Liverpool None L12 2 AP
    Phone #: +44- (0-) 1512525696
    800 #: --
    e-mail: cfgd@liv.ac.uk
    Home page: http://www.liv.ac.uk/cfgd/
  • Cooley's Anemia Foundation, Inc.
    330 7th Ave
    New York NY 10001
    Phone #: 212-279-8090
    800 #: 800-522-7222
    e-mail: info@cooleysanemia.org
    Home page: http://www.cooleysanemia.org
  • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
    150 Custer Court
    Green Bay WI 54301-1243
    Phone #: 920-336-5333
    800 #: 877-336-5333
    e-mail: mums@netnet.net
    Home page: http://www.netnet.net/mums/
  • Madisons Foundation
    PO Box 241956
    Los Angeles CA 90024
    Phone #: 310-264-0826
    800 #: N/A
    e-mail: getinfo@madisonsfoundation.org
    Home page: http://www.madisonsfoundation.org
  • March of Dimes Birth Defects Foundation
    1275 Mamaroneck Avenue
    White Plains NY 10605
    Phone #: 914-428-7100
    800 #: 888-663-4637
    e-mail: Askus@marchofdimes.com
    Home page: http://www.marchofdimes.com
  • NIH/National Heart, Lung and Blood Institute Information Center
    P.O. Box 30105
    Bethesda MD 20824-0105
    Phone #: 301-592-8573
    800 #: --
    e-mail: nhlbiinfo@rover.nhlbi.nih.gov
    Home page: N/A
  • Seed of Life Philanthropic Organization
    P.O.Box 73564
    Ontario None M6C 1C0
    Phone #: (41-6) -745-4267
    800 #: N/A
    e-mail: info@seedoflifepo.org
    Home page: http://www.seedoflifepo.org
  • Sickle Cell Association of Ontario
    3199 Bathurst Street
    Ontario None M6A 2B2
    Phone #: 416-789-2855
    800 #: --
    e-mail: sicklecell@look.ca
    Home page: http://www.sicklecellontario.com
  • Sickle Cell Disease Association of America, Inc.
    16 S. Calvert St
    Baltimore MD 21202
    Phone #: 410-528-1555
    800 #: 800-421-8453
    e-mail: scdaa@sicklecelldisease.org
    Home page: http://www.sicklecelldisease.org
  • Sickle Cell Disease Association of Piedmont
    1102 East Market Street
    Greensboro NC 27420
    Phone #: 336-274-1507
    800 #: 800-733-8297
    e-mail: scdap@scdap.org
    Home page: http://www.scdap.org



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html