Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Thalassemia Major


Synonyms of Thalassemia Major
  • Beta Thalassemia Major
  • Cooley's Anemia
  • Erythroblastotic Anemia of Childhood
  • Hemoglobin Lepore Syndromes
  • Hereditary Leptocytosis, Major
  • Mediterranean Anemia
  • Microcythemia
  • Target Cell Anemia
  • Thalassemia, Major

Disorder Subdivisions



    General Discussion
    Thalassemia major is a rare blood disorder characterized by a marked increase in F hemoglobin and a decrease in the production of certain oxygen carrying proteins in red blood cells (beta polypeptide chains in the hemoglobin molecule). Thalassemia major is the most severe form of chronic familial anemias that result from the premature destruction of red blood cells (hemolytic). This disease was originally found in people living near the Mediterranean Sea. People with this disorder also have a reduced number of circulating red blood cells (erythrocytes). Thalassemia major is inherited as an autosomal recessive trait.
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    Organizations related to Thalassemia Major
    • Anemia Institute for Research and Education
      151 Bloor Street West
      Toronto, Ontario None M5S 1S4
      Phone #: 416--96-9-7431
      800 #: 877--99-2-6364
      e-mail: info@anemiainstitute.org
      Home page: http://www.anemiainstitute.org
    • Children's Cancer & Blood Foundation
      333 East 38th Street
      New York NY 10016-2745
      Phone #: 212-297-4336
      800 #: --
      e-mail: info@childrenscbf.org
      Home page: http://www.childrenscbf.org/
    • Cochrane Cystic Fibrosis and Genetic Disorders Review Group
      Institute of Child Health
      Liverpool None L12 2 AP
      Phone #: +44- (0-) 1512525696
      800 #: --
      e-mail: cfgd@liv.ac.uk
      Home page: http://www.liv.ac.uk/cfgd/
    • Cooley's Anemia Foundation, Inc.
      330 7th Ave
      New York NY 10001
      Phone #: 212-279-8090
      800 #: 800-522-7222
      e-mail: info@cooleysanemia.org
      Home page: http://www.cooleysanemia.org
    • MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
      150 Custer Court
      Green Bay WI 54301-1243
      Phone #: 920-336-5333
      800 #: 877-336-5333
      e-mail: mums@netnet.net
      Home page: http://www.netnet.net/mums/
    • March of Dimes Birth Defects Foundation
      1275 Mamaroneck Avenue
      White Plains NY 10605
      Phone #: 914-428-7100
      800 #: 888-663-4637
      e-mail: Askus@marchofdimes.com
      Home page: http://www.marchofdimes.com
    • NIH/National Heart, Lung and Blood Institute Information Center
      P.O. Box 30105
      Bethesda MD 20824-0105
      Phone #: 301-592-8573
      800 #: --
      e-mail: nhlbiinfo@rover.nhlbi.nih.gov
      Home page: N/A
    • Sickle Cell Disease Association of America, Inc.
      16 S. Calvert St
      Baltimore MD 21202
      Phone #: 410-528-1555
      800 #: 800-421-8453
      e-mail: scdaa@sicklecelldisease.org
      Home page: http://www.sicklecelldisease.org
    • Sickle Cell Disease Foundation of California
      6133 Bristol Parkway #240
      Culver City CA 90230
      Phone #: 310-693-0247
      800 #: N/A
      e-mail: N/A
      Home page: http://www.scdfc.org
    • Sj?ldne Diagnoser / Rare Disorders Denmark
      Frederiksholms Kanal 2, 3rd Floor
      Copenhagen K None 1220
      Phone #: 45 -33 -14 00 10
      800 #: N/A
      e-mail: mail@sjaeldnediagnoser
      Home page: http://www.raredisorders.dk



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html