Diseases & Conditions


A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Walker Warburg Syndrome


Synonyms of Walker Warburg Syndrome
  • Cerebroocular Dysgenesis
  • Cerebroocular Dysplasia-Muscular Dystrophy Syndrome
  • Chemke Syndrome
  • COD
  • COD-MD Syndrome
  • HARD +/-E Syndrome
  • HARD Syndrome
  • Hydrocephalus, Agyria, and Retinal Dysplasia
  • Pagon Syndrome
  • Warburg Syndrome
  • WWS

Disorder Subdivisions



    General Discussion
    Walker-Warburg syndrome (WWS) is a rare genetic multisystem disorder characterized by muscle disease and brain and eye abnormalities. The specific symptoms and severity of WWS vary greatly from case to case. The most consistent features are a smooth appearance of the surface of the brain due to lack of normal folds (lissencephaly), malformations of other brain structures (cerebellum and brain stem), various developmental abnormalities of the eyes, and progressive degeneration and weakness of the voluntary muscles (congenital muscular dystrophy). WWS is inherited as an autosomal recessive trait.

    WWS is considered a form of muscular dystrophy, which is a group of disorders characterized by weakness and atrophy of various voluntary muscles of the body. Approximately 30 different disorders make up the muscular dystrophies. The disorders affect different muscles and have different ages of onset, severity and inheritance patterns.

    Organizations related to Walker Warburg Syndrome
    • Cure CMD (Congenital Muscular Dystrophy)
      P.O. Box 701
      Olathe KS 66051
      Phone #: N/A
      800 #: 866-400-3626
      e-mail: info@curecmd.com
      Home page: http://www.curecmd.org
    • Guardians of Hydrocephalus Research Foundation
      2618 Avenue Z
      Brooklyn NY 11235
      Phone #: 718-743-4473
      800 #: 800-458-8655
      e-mail: GHRF2618@aol.com
      Home page: N/A
    • Hydrocephalus Association
      870 Market Street
      San Francisco CA 94102
      Phone #: 415-732-7040
      800 #: 888-598-3789
      e-mail: pip@hydroassoc.org
      Home page: http://www.hydroassoc.org
    • Lissencephaly Network, Inc.
      10408 Bitterroot Ct
      Fort Wayne IN 46804
      Phone #: 219-432-4310
      800 #: --
      e-mail: lissencephalyOne@aol.com
      Home page: http://www.lissencephaly.org/
    • National Hydrocephalus Foundation
      12413 Centralia
      Lakewood CA 90715-1623
      Phone #: 562-924-6666
      800 #: 888-857-3434
      e-mail: nhf@earthlink.net
      Home page: http://www.nhfonline.org
    • National Institute of Neurological Disorders and Stroke (NINDS)
      31 Center Drive
      Bethesda MD 20892-2540
      Phone #: 301-496-5751
      800 #: 800-352-9424
      e-mail: braininfo@ninds.nih.gov
      Home page: http://www.ninds.nih.gov/



    For a Complete Report

    This is an abstract of a report from the National Organization for Rare Disorders, Inc. ? (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html